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Dr. Howenstein notes how any "sugar substitute … made in a factory [he specifically notes Nutrasweet (aspartame), Sucralose, and Splenda] … is dangerous to health. Many of these contain chlorine. The best safe sweetening substance appears to be the natural substance stevia. Several of the glycosides in stevia have blood sugar lowering capability."
Further, Dr. Patrick B. Massey noted in the Daily Herald (May 20, 2002) that, "Stevia has some very interesting properties. It has no calories but has actions similar to several currently used medications. It stimulates the release of insulin and normalizes the response to glucose, especially in type 2 diabetes. It is used in Latin America as an inexpensive therapy for hyperglycemia."