Originally posted by rhinoceros
Originally posted by Semicollegiate
LUCA is presumed to have exsisted because the DNA-Amino Acid transcription and transfer proccess is identical in all living organisms.
DNA-protein process is far from identical between the 3 different domains of life. For example in archaea and bacteria you've got coupled
transcription and translation. In eukarya you don't. In eukarya and archae you've got introns. In bacteria you don't (apart from this special
self-splicing type that is also present in eukarya). In bacteria and archaea you've got polycistronic mRNA. In eukarya you don't. In bacteria
you've got sigma factors. In eukarya you don't. I can't remember how it's for archaea. Ribosomes are far from identical between archaea, bacteria
and eukarya. For example in bacteria and archaea you've got the 16S subunit. In eukarya you have the 18S. Even the genetic code (of codons) isn't
universal. These are just some examples that come to my mind. AFAIK currently it's assumed that LUCA's genome was probably an RNA one. Also during
early days viruses transferred a lot of stuff horizontally between the 3 lineages.
Good call, I was sloppy again.
I meant, specifically, the universality of the genetic code. Tranfer RNA uses the same codons for the various (commonly 22) amino acids in 99.9...
% of living organisms.
The transcription process copies the whole gene like video or audio tape and isn't affected by the codon size, although I suspect there are
more
similarities than differences in the DNA ( or RNA) replication, translation and transfer processes as a whole.
Using evolution as a guide, the oldest genes are in energy production, protien synthesis, and nucleic acid maintenance. Viruses know our nuclei
pretty well and could be the basic cause of our nuclei. Mitochondria produce most of our energy and appearently have some differences in their codon
spelling, as compared to most organisms. So I would guess that the genes we have in common with LUCA would be protien synthesis genes or cytoplasmic
glycolysis genes.
If LUCA was pre Oxygen Extinction Event then maybe we have no genes in common with it at all.
Did the Oxygen Extinction Event cause the change to DNA from RNA?
Interesting difference you site about bacteria. Could you "download" cellulosic enzyme genes into a bacteria? Maybe half of a cellulosic emzyme
into each of two different cultures so the bacteria won't digest themselves. Do bacteria have no inert DNA at all, or no inert DNA within each
gene?