Stalin's half-man, half-ape super-warriors, page 3
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reply posted on 27-12-2005 @ 05:03 PM by StellarX
Originally posted by mad scientist
Ahem, It is my understanding that humans have 23 base pairs in our DNA whereas Apes and Chimps have 24. Therefore making it impossible. Out.


Well please check out these links and see if you still feel that you should be using that horrible word.

Animal-Human Hybrids Spark Controversy

"For example, faulty human heart valves are routinely replaced with ones taken from cows and pigs. The surgery—which makes the recipient a human-animal chimera—is widely accepted. And for years scientists have added human genes to bacteria and farm animals."

"What's caused the uproar is the mixing of human stem cells with embryonic animals to create new species"

"Cynthia Cohen is a member of Canada's Stem Cell Oversight Committee, which oversees research protocols to ensure they are in accordance with the new guidelines.

She believes a ban should also be put into place in the U.S.

Creating chimeras, she said, by mixing human and animal gametes (sperms and eggs) or transferring reproductive cells, diminishes human dignity."

U.S. Denies Patent for a Too-Human Hybrid

"A New York scientist's seven-year effort to win a patent on a laboratory-conceived creature that is part human and part animal ended in failure Friday, closing a historic and somewhat ghoulish chapter in American intellectual-property law.

"The U.S. Patent and Trademark Office rejected the claim, saying the hybrid -- designed for use in medical research but not yet created -- would be too closely related to a human to be patentable."

Newman's application, filed in 1997, described a technique for combining human embryo cells with cells from the embryo of a monkey, ape or other animal to create a blend of the two -- what scientists call a chimera. That's the Greek term for the mythological creature that had a lion's head, a goat's body and a serpent's tail."

Human cloning from human cell and cows egg.

"the world's first human clone of an adult has now been made, by an American biotechnology company in Massachusetts, Advanced Cell Technology. They took a cell from Dr Jose Cibelli, a research scientist and combined it with a cows egg from which the genes had already been removed. (News November 1998)

The genes activated and the egg began to divide in the normal way up to the 32 cell stage at which it was destroyed. If the clone had been allowed to continue beyond implantation it would have developed as Dr Cibelli's identical twin. Technically 1% of the human clone genes would have belonged to the cow - the mitochondria genes. Mitochondria are power generators in the cytoplasm of the cell. They grow and divide inside cells and are passed on from one generation to another. They are present in sperm and eggs. Judging by the successful growth of the combined human-cow clone creation it appears that cow mitochondria may well be compatible with human embryonic development."

People Are Human-Bacteria Hybrid.

"Most of the cells in your body are not your own, nor are they even human. They are bacterial. From the invisible strands of fungi waiting to sprout between our toes, to the kilogram of bacterial matter in our guts, we are best viewed as walking "superorganisms," highly complex conglomerations of human cells, bacteria, fungi and viruses.

That's the view of scientists at Imperial College London who published a paper in Nature Biotechnology Oct. 6 describing how these microbes interact with the body. Understanding the workings of the superorganism, they say, is crucial to the development of personalized medicine and health care in the future because individuals can have very different responses to drugs, depending on their microbial fauna.

The scientists concentrated on bacteria. More than 500 different species of bacteria exist in our bodies, making up more than 100 trillion cells. Because our bodies are made of only some several trillion human cells, we are somewhat outnumbered by the aliens. It follows that most of the genes in our bodies are from bacteria, too."

Hybrid Humans?

Analysis of the skeletal remains of a four-year-old child buried some 25,000 years ago in a Portuguese rock-shelter suggests early modern humans and Neandertals may have interbred.

Well just ask if you want some more links.

Stellar

[edit on 27-12-2005 by StellarX]


reply posted on 26-1-2006 @ 09:44 PM by lordmagnus
To accomplish this feat, all one would need is about $1000 worth of lab equipment, and the appropriate specimens. It has been done in the petri dish, using donated human ova, and chimpanzee sperm. There is only 1 chromosome count differance between humans, chimpanzees, and gorillas. They actually have 1 more chromosome than humans, in our evolutionary past, our common ancestors had two chromosomes that fused together forming chromosome #2 in humans, the chimps and gorillas stayed the same in that respect, thus have 1 more than us. You can succesfully crossbreed animals with far greater differances; Tigers and Lions (tygon and ligers), sheep and goats (geeps, shoats), etc. actually sheep and goats have several chromosome differances, although this leads to sterile offspring.
The procedure used to get the sperm and ova together is simply called semen processing (sperm washing). It consists of mixing the collected semen with an equal ammount of sterile, buffered, isotonic saline, glycerine, and egg yold extract (nutrient), dextrose (nutrient) at about PH 7.1 with the semen, and gently shakeing the mix for a short period. Then the mix is run through a centrifuge, and the sperm settle to the bottom as a small pellete. This is draw off with a pipette, and then either examined for quality control, or mixed with the ova in a petri dish. Alternativly one could also perform an I.U.I procedure with the processed pellete (interuterine insemination).
The sperm washing is done to remove white blood cells, and anti-bodies that could stimulate an immune system response in the egg, or the hosts body. The one time it has been done in a petri dish, the two scientists decided to destroy the dividing cells after 8 or 12 divisions due to ethical concerns. Supposedly a member of PETA had infiltrated a private lab in central mexico where a hybrid child was born from a invitro procedure done with chimpanzee semen, it is claimed that it has to be given mood stabiizers and other anti psychotics, and is continuously depressed due to malformations of the brain (this may all be untrue).

EQUIPMENT NEEDED:
Centrifuge (try chinese made lab equipment) $270 or so for a nice model
Pipettes (1ml, 2ml, 10ml) $2.00 a piece new and used
Pipette pumps/fillers $15.00-$40.00 brand new (look around)
microscope w/mech. stage 1500X mag. $300 (again chinese equipment)
petri dishes $7.00 glass, $2.00 plastic ea (lab supplie everywhere)
testtubes $.25-$2.00 ea (anywhere just about)
syringes (for reimplantation) .50-$2.00 ea
1mm I.D. polyethylene tubing $15.00 10' roll

prob. missed a few things on that list, get creative!


reply posted on 2-2-2006 @ 05:20 AM by orca71
Originally posted by Nakash
Human DNA is NOT 99.99% accurate with Chimp DNA. That's a misconception due to an innacurate method of splicing genes and putting the Nucleotides back together. According to this method, the simplest prokaryote has 99% similar DNA to humans. The single biggest problem with the method is that it doesn't distinguish between our useless 90-98% DNA introns obtained via Viral infections and then transmitted throughout generations, and the "true" DNA used for translation and transcription.

[edit on 21-12-2005 by Nakash]


Im pretty sure they were talking about what you refer to as "true" DNA, or exons but I cant be sure since I havent read the actual report or done my own testing. In fact, Im not even sure who came up with those numbers.

However one thing we do know is that it's fairly easy to mix DNA from different sources, even plants and animals, and after a bit of trial and error, have a successful product. We even know unusual chromosome counts can be supported successfully to create completely new classes of creatures. Mixing ape and human DNA is relatively easy once you've mapped the genes and allocated attributes. Fortunately, Stalin's people had no clue about DNA. Unfortunately the world is full of well funded labs in the darkest (no pun intended) corners of the world where laws aren't quite as strict as they are here in the US. In fact in many countries there are no laws whatsoever that address these issues and where they are a part of an internation agreement there is no active investigation and enforcement.

Now that working with DNA is fairly standard and affordable technology (I can put together a decent lab for <50k from the internet, or even less if I do some of my own fabrication/assembly), who knows what kind of abominations we will witness during the next 50 years.


reply posted on 2-2-2006 @ 05:32 AM by orca71
Originally posted by lordmagnus

EQUIPMENT NEEDED:
Centrifuge (try chinese made lab equipment) $270 or so for a nice model
Pipettes (1ml, 2ml, 10ml) $2.00 a piece new and used
Pipette pumps/fillers $15.00-$40.00 brand new (look around)
microscope w/mech. stage 1500X mag. $300 (again chinese equipment)
petri dishes $7.00 glass, $2.00 plastic ea (lab supplie everywhere)
testtubes $.25-$2.00 ea (anywhere just about)
syringes (for reimplantation) .50-$2.00 ea
1mm I.D. polyethylene tubing $15.00 10' roll

prob. missed a few things on that list, get creative!


Thank goodness for the chinese and their high-quality but low-cost products.

If we have a full data-set and have devised a procedure, we would also need a secure environment with HVAC for multiple rooms including an infirmary, a refrigerator, a freezer, a microwave, incubators, staff (including medically trained with medical equipment). We may need some clearning supplies and equipment as well. In a "3rd world" country, this can all be done relatively cheaply, not that I would advocate such a thing, so I would be surprised if more bizarreness doesnt reveal itself more often in the future.

ps. I forgot to add a coffee-maker, half-and-half, non-dairy creamer, sugar and tea-bags. Anything else is up to the staff to bring in themselves. Its probably a good idea for the staff to have a seperate refrigerator.

[edit on 2-2-2006 by orca71]

Oh yeah, I forgot the coffee. What good is a coffee-maker without coffee?

[edit on 2-2-2006 by orca71]
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