reply to post by Krakatoa
I don't know about Unisom, but the occasional Benadryl sure works for me. No drowsiness and, it's a great (though short-acting, and with easily
built-up resistance) SSRI. So it improves mood the day after, almost as good as sex!
Seriously, though, I do not think the FDA's decision can be taken at face value. Best case scenario, IMO, is they are doing the right thing for a
change -- because given their real agenda, they can afford to. In politics as usual, it sometimes pays to be truthful and/or do the right thing, if
only because that obfuscates all the lies and malfeasance that predominate.
Let us assume they are doing the right thing -- reducing dosages because of harmful and/or dangerous side effects like drowsiness. That may also
further evil agendas in the background such as encouraging off-label usage of antipsychotics (which have a host of harmful side effects like weight
gain, diabetes, reduced intelligence etc. etc.) but which, as it happens, do cause most people to sleep more deeply and longer.
Or there may be other, patentable alternatives in the FDA approval pipeline that, similar to antipsychotics, do not have mood-altering or addictive
potentials like the benzodiazapenes do, but nonetheless conk you out (never mind other side effects, e.g., suicidal ideation, weight gain, diabetes,
etc. etc.) By reducing dosages of existing sleep aids (many of the most popular being benzodiazapenes), the FDA indirectly encourages their
side-by-side use with newer (and in some ways, much more dangerous) "alternatives" like those aforementioned.
It is always in BIg Pharma's best interest to promote the use of new medications, no matter how harmful -- because patents, and patents alone, mean
big profits for them. The trend nowadays is to promote substances that flatten affect and/or mood generally, but have no compensatory euphoric (i.e.,
dopamine -pathway) activity and therefore less risk of addiction or abuse. And such substances tend to be highly toxic, even if effective for mood
disorders or insomnia.
My rule of thumb, when it comes to pharmaceuticals that depress (or stimulate) the CNS, is the older (and longer-expired) the patent, and the more
addictive the substance, the safer (ironically) it tends to be. That is, as long as one is not an addict. The ones that are non-addictive, and that
would include some of the new sleep remedies as well as drugs used to treat depression, bipolar disorder, schizophrenia as well as ADD/ADHD, tend to
require higher dosage by weight, are more liver-toxic, and carry higher risk of lethality, not to mention other secondary side effects, known and
My rules of thumb are, never trust the FDA, and avoid any prescription drug approved by them after 1970 as if it were pus from a Black Plague victim.
And as much as possible, avoid prescription drugs altogether!