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BACKGROUND: In most tuberculosis (TB) endemic countries, bacillus Calmette-Guérin (BCG) is usually given around birth to prevent severe TB in infants. The neonatal immune system is immature. Our hypothesis was that delaying BCG vaccination from birth to 10 weeks of age would enhance the vaccine-induced immune response.
METHODS: In a randomized clinical trial, BCG was administered intradermally either at birth (n=25) or at 10 weeks of age (n=21). Ten weeks after vaccination, and at 1 year of age, vaccine-specific CD4 and CD8 T cell responses were measured with a whole blood intracellular cytokine assay. RESULTS: Infants who received delayed BCG vaccination demonstrated higher frequencies of BCG-specific CD4 T cells, particularly polyfunctional T cells co-expressing IFN-gamma, TNF-alpha and IL-2, and most strikingly at 1 year of age.
CONCLUSIONS: Delaying BCG vaccination from birth to 10 weeks of age enhances the quantitative and qualitative BCG-specific T cell response, when measured at 1 year of age
BCG vaccine is given at birth "to babies who are more likely to come into contact with Tuberculosis than the general population."
The BCG vaccine is thought to offer protection for around 15 years. But it is not effective for everyone. In the UK, only around two thirds of those who receive the vaccination are believed to be protected. Some trials have suggested protection could be as low as 30%
please take the time to read both links they include much more info.
Efficacy
In the world's largest and only double-blind vaccine trial of BCG vaccine in India, the incidence of TB was higher in the vaccinated group then in the control group.
The New Scientist wrote: "the world's biggest trial to assess the value of BCG tuberculosis vaccine has made startling revelation that the vaccine does not give any protection against bacillary forms of tuberculosis." (5)
The Lancet (14 March 1992) also carried out a study of 83,000 people who had been vaccinated against TB and concluded that they could find no statistically significant protection by the BCG vaccine against tuberculosis. (6) Holland does not have a BCG programme, and they have the lowest TB death rate in Europe. (5)
They don't know how or if it works
In the book `Vaccines' by Plotkin and Mortimer, under the heading `Efficacy of Bacille Calmette-Guerin' it states:
"The true effectiveness of BCG vaccine has been debated for decades. Large clinical trials from the 1930's and through the 1970's yielded wide ranging and conflicting results, demonstrating efficacy from 0 to 80%. The most recent trial in India only served to continue the argument".even after years of study and debate, the question `does BCG work?' cannot be answered definitely."
Also:
"The exact immune response elicited by BCG vaccination and its mechanism of action within the host are not well understood"..Studies of the immunological events that occur within the human host after BCG vaccination are almost totally lacking".both animal data and human clinical studies have provided information about the immune response to BCG, yet no vaccine so widely used is so little known about its mechanisms of action.
The immunology is complicated and development of an assay has been hampered by the lack of understanding".given our incomplete understanding of tuberculosis immunology, we are left with imperfect indicators of immunity." (12)
Side effects
Rash, fever, local induration, pain and lymphadenopathy, discharging ulcer, abcess formation, anaphylactic shock, lymphadenitis, difficulty in breathing, nausea, vomiting, phlyctenular conjunctivitis, draining sinuses, death.
In 1930, 73 children were killed by BCG vaccine in a few months. A book by Dr. Neville Irvine, "BCG Vaccination in Theory and Practice" reports of this disaster.
There had been a similar number of deaths in Spain when the Association of Spanish Pediatricians told their members not to use the vaccine. (7, 8, 9 and 10) A report in the Medical Monitor (June 1992) also stated that the vaccine can give you TB!
"It can cause disseminated TB in immuno-suppressed individuals, including children, and local ulceration and osteitis (wasting away of the bone) appears to be more common in babies."
Complication rates for serious side effects (from the vaccine) were recorded at 3-6 children per 200 (1.5% - 3%). (4)
SOURCE:www.vaclib.org...
Many people do not realize that tuberculosis is unheard of in unvaccinated populations.
"Note: James Phipps, the eight-year-old boy initially vaccinated by Jenner in 1796, was re-vaccinated 20 times, and died at the age of twenty. Jenner's own son, who was also vaccinated more than once, died at twenty-one. Both succumbed to tuberculosis, a condition that some researchers have linked to the smallpox vaccine." [Favez, G, "Tuberculous Superinfection Following a Smallpox Re-Vaccination", Praxis, July 21, 1960; 49:698-699; Ambs, E et al, "Tuberculous Abscess of the Upper Arm With Regional Lymphadenitis as a Consequence of Injection in Two Siblings", Med Klin, July 7, 1967, 62:1050-1054; Eleanor McBean, The Poisoned Needle (Mokelumne Hill, CA : Health Research, 1974) pp. 28-29, 66] (p. 46)
Originally posted by Grifter81
reply to post by jrmcleod
Does this depend on the NHS trust your under? Either that or it's a very recent stance on behalf of the health service. I'm in North West England, Cumbria to be exact. My son was born on the 6th January last year and there was no mention of this.
I wouldn't have allowed them to give him the BCG right after birth. It seems too soon, but like you I was unaware TB was such a problem these days.
Originally posted by Silcone Synapse
reply to post by jrmcleod
My sisters baby was given the BCG when she was one,about 5years back,as she was going overseas to visit family.
The doctors said it was the same jab you get in school when you are 12 or so,as their is no "low dose" vaccine for babies.
The poor girl developed asthma within 3 weeks of that jab,and has been hospitalized more than a few times since.
She had never had any chest complaints before that jab.
Now I am not saying the jab is 100% responsible,but I am not saying it wasn't either.
Just do as much research on the BCG first,before you go ahead and have it given to your new born child.
In hindsight,my sister says she would not have given her the jab,as she blames it on the asthma.
Best of luck with your new baby!
London has the highest TB rate of any capital city
Originally posted by jrmcleod
Recently my partner found out that she was pregnant with out second child. She went for her first Midwife appointment and was given all her paperwork etc and the "drills" regarding blood testing and scans etc were explained.
Since this is our second child in 3 years, we already knew the information but to our surprise we were informed of a new practice that wasn't around in 2009 at the birth of our first child, and its being blamed on immigration.
The new procedure is that ALL newborns are given the BCG vaccine for TB. The midwife explained that this would be given no later than 6 hours after birth and that it would leave scarring on the child but its OK to give it at that young an age because the child doesn't really feel pain. My partner (who is a Pediatric Nurse) asked why the rules have changed. Prior to this, here in the UK, the BCG vaccine was given to children when at school, around the age of 11-14. The midwife explained that the rate of increase of cases of TB in the UK had risen so much due to mixed parental parents i.e. Asians, Europeans, Africans etc and that TB was being taken over here by immigrants and it was becoming a serious issue. She the proceeded to ask my partner is she and I would consent to this and my partner said no. My partner explained that we both feel that the Vit K injection at birth is sufficient and that we'd rather not inject our child with the BCG at such an early age.
I was shocked to say the least that this new procedure has been introduced. With this information and notion, i decided to do some research.
BACKGROUND: In most tuberculosis (TB) endemic countries, bacillus Calmette-Guérin (BCG) is usually given around birth to prevent severe TB in infants. The neonatal immune system is immature. Our hypothesis was that delaying BCG vaccination from birth to 10 weeks of age would enhance the vaccine-induced immune response.
METHODS: In a randomized clinical trial, BCG was administered intradermally either at birth (n=25) or at 10 weeks of age (n=21). Ten weeks after vaccination, and at 1 year of age, vaccine-specific CD4 and CD8 T cell responses were measured with a whole blood intracellular cytokine assay. RESULTS: Infants who received delayed BCG vaccination demonstrated higher frequencies of BCG-specific CD4 T cells, particularly polyfunctional T cells co-expressing IFN-gamma, TNF-alpha and IL-2, and most strikingly at 1 year of age.
CONCLUSIONS: Delaying BCG vaccination from birth to 10 weeks of age enhances the quantitative and qualitative BCG-specific T cell response, when measured at 1 year of age
Source
Now, unless I'm wrong, i didn't realise the UK was in an epidemic state with TB. This information also states that evidence suggests that giving the BCG vaccine at 10 weeks is more beneficial to the efficiency of the vaccine...so why give it at birth?
BCG vaccine is given at birth "to babies who are more likely to come into contact with Tuberculosis than the general population."
From Wikipedia
Now there are NO mixed marriages or children in my family, nor do we have any friends with mixed parents. Our risk is NOT any greater than the general public's. So why are they taking this stance? What do the NHS know that we don't?
The BCG vaccine is thought to offer protection for around 15 years. But it is not effective for everyone. In the UK, only around two thirds of those who receive the vaccination are believed to be protected. Some trials have suggested protection could be as low as 30%
Does this mean my child will need a second shot at school when he/she is 15?
Source
What are your thoughts on this? Can the NHS take the stance that this procedure is based on immigration into the UK? All i can say is thank goodness the NHS require parental permission here in the UK before they can do these things...
NHS BCG Information For New-Borns
Originally posted by jrmcleod
reply to post by jameshawkings
I'm afraid it isn't solely for the London Area. This is most definitely here in the remote North East of Scotland too.