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Oh I've Gone Crosseyed...
The moment is near, I believe, when, by means of a deliberately paranoid thought process (as through automatism and other passive states), it will be possible to systematize confusion and contribute to the total discrediting of the world of reality.
Since many proteins that bind DNA recognize specific sequences of bases, it is not surprising that most bind to the floor of the major groove, as this provides more chemical information for recognition than the minor groove......
......A unique property of PNA is its ability to displace one strand of a DNA double-helix.
Triplet–singlet spin communication between DNA nucleotides serves the basis for quantum computing.
Chemical Physics Letters; Feb2007, Vol. 436 Issue 1-3, p258-262, 5p
The nature of spin communication between DNA nucleotide pairs is discussed. The results are based on CIU (2×106 configurations, 6-311G∗∗ basis set) quantum chemistry computations at a constant temperature T =310K of complementary nucleotide pairs, guanosine–cytidine (G–C) and adenosine–thymidine (A–T) monophosphates, assembled into DNA fragments of different length. Calculations reveal alternation of low energy triplet–singlet (T–S) potential energy surfaces (PESs), assigned to individual nucleotides. In a narrow energy interval these PESs approach, showing repulsion and uncommon crossings. Complementary nucleotide pairing, a result of Watson–Crick hydrogen bonding, produces a global minimum in total energy, coming from the unique crossing between two singlet by nature PESs strictly around 310K. Interaction between non-complementary nucleotides reveals no minima and points rather to system destabilization. Computations show that regularly organized DNA is a structure of similarly oriented spins along each of its two chains, so that the resultant spin of the whole structure is equal to zero. Disordering in spin structure produces coherent effects, appearing in spin flipping, which serves the basis for constructing DNA-based quantum computing. [Copyright &y& Elsevier]