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It came down in the Yaftabad district in the south of the capital Tehran.
The building is reported to be in flames and emergency services are on the scene.
State radio has reported that at least 10 people have been killed.
The plane is believed to have just taken off from the city's Mehrabad airport, which handles domestic, international and military flights.
A report on state television said the plane suffered a "technical problem" immediately after take-off.
The city is currently enveloped in a thick blanket of fog.
A civil aviation official said: "There were between 74 and 90 people on board."
Originally posted by Nventual
Was it an accident, or was it an attack?
Originally posted by asala
all people on the plane are thought to have been killed says the mayor of iran
Originally posted by thematrix
I'm kinda wondering how long it takes before someone sais that this was an Iranian military training run for 9/11 attacks.
[edit on 6/12/05 by thematrix]