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Originally posted by Luther777
In most cases, "no". That's all part of the conspiracy. Why aren't more studies being done on these?
It sounds almost too good to be true: a cheap and simple drug that kills almost all cancers by switching off their “immortality”. The drug, dichloroacetate (DCA), has already been used for years to treat rare metabolic disorders and so is known to be relatively safe.
Until now it had been assumed that cancer cells used glycolysis because their mitochondria were irreparably damaged. However, Michelakis’s experiments prove this is not the case, because DCA reawakened the mitochondria in cancer cells. The cells then withered and died (Cancer Cell, DOI: 10.1016/j.ccr.2006.10.020).
As the scientists have understood the precise role of the gene in normal cell division, they are now planning to test their theory on cancer cells.
“Unlike some other genes that become mutated in cancer cells, the Bub 1 gene appears normal indicating that it behaves in exactly the same way in cancer cells as it does in healthy cells,” Dr. Taylor said.
“If this is the case, then we can be confident that switching it off will stop cancer cells proliferating too. And while our normal cells don’t divide that often, cancer cells divide more frequently, so hopefully by targeting Bub1 we will selectively kill cancer cells,” he added.
The research, which began in 1999, has been published in the journal Developmental Cell. (ANI)