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originally posted by: puzzled2
a reply to: Kurokage
good link shows for the last 400-500 years the experts stop believing in a flat earth.
Belief in a flat Earth among educated Europeans was almost nonexistent from the Late Middle Ages onward,
Let's pretend is doesn't mean that for thousands of years before then they believed in the flat earth.
Just like the Flat earthers of old your science of mRNA safety is fool proof - But without any real proof it's all guess work.
Anyone seen the results of the Sars-cov-2 challenge trials yet?
he knows exactly what he’s talking about. You fools won’t ever admit the vaccine kills and sucks, but it does.
The global burden of sepsis is estimated at up to 19 million cases annually killing 5 million mainly in low income countries. The infection affects 1.7 million Americans a year and kills more than 250,000, making it one of the top 10 causes of death. In Australia more than 5,000 die from sepsis each year and it contributes to up to a half of all hospital deaths.
A paper published today in the Journal of the American Medical Association by Monash researchers comprehensively quashes the idea that the vitamin C-based cocktail has any positive impact on patients with sepsis.
Sepsis is the body's overreaction to a severe infection, leading to multiple organ failure and, frequently, death.
Results: Six randomized controlled trials (RCTs) and seven observational studies enrolling 1,559 patients were included (762 were treated with HAT, and 797 were treated with hydrocortisone alone, standard care or placebo). HAT therapy was associated with significant reductions in duration of vasopressor use (mean differences [MD], -14.68, [95% CI, -24.28 to -5.08], P = 0.003) in RCTs, but not in observational studies (MD, 11.21 [95% CI, -44.93 to 67.35], P = 0.70). HAT therapy was associated with less organ dysfunction at 72 h both in RCTs (MD, -0.86 [95% CI, -1.32 to -0.40], P < 0.001) and observational studies (MD, -2.65 [95% CI, -5.29 to -0.01], P = 0.05). HAT therapy was associated with lower hospital mortality and higher PCT clearance in observational studies. Similar results for the primary outcome were found in the sensitivity analysis. TSA results suggested more trials to reach the required information size.
Conclusion: Among patients with sepsis and septic shock, a combination therapy of hydrocortisone, ascorbic acid, and thiamine, compared with placebo, could reduce the duration of vasopressor use and SOFA scores during the first 72 h.
According to Professor Bellomo, the study provides high quality evidence that, in patients with septic shock, the combination of high dose intravenous vitamin C, thiamine and hydrocortisone is not superior to usual care with hydrocortisone alone:
The guy is a complete quack.
I don't want to live in some echo chamber or bubble where everyone kisses each others butt. In looking for the truth of how and why our reality is the way it is does suck at times. If there is some path out of this mess we need to know where we are and where we want to go.
originally posted by: Kurokage
a reply to: asabuvsobelow
The difference is that Dr Marik altered and falsified results whilst also offering drugs outside his remit
Snopes.com
Well, here's a more recent counter to the Spin article..
originally posted by: ManBehindTheMask
And yet for tens of thousands of us that were literally knocking on what seemed like deaths door and our personal physicians insisting on a redefine of ivermectin it turned us around very quickly
In my case less that 24 hours and they were threatening a forced vent on me
Glad my doc stepped in
originally posted by: Oldcarpy2
I think describing Dr Malone as the "founder and inventor" of MRNA tech is not completely accurate.
Here is an interesting article about the actual history of it.
Posting just because things are actually a little more complex and because it's an interesting article:
originally posted by: Xtrozero
originally posted by: ManBehindTheMask
And yet for tens of thousands of us that were literally knocking on what seemed like deaths door and our personal physicians insisting on a redefine of ivermectin it turned us around very quickly
In my case less that 24 hours and they were threatening a forced vent on me
Glad my doc stepped in
I call BS to your 10,000s BTW. So here we are 2+ years later after the initial ivermectin push that we have now massive amounts of REAL clinical trials data that show that it really doesn't help in the end. I'm not here to change your beliefs,. but real data is real data...
You can't just cheery pick what fits your narrative like maybe some Brazilian study in the past and then not follow up on it that showed there were some big inconsistencies in the trails in how they accomplished it and incorrect reporting. I remember that one and hoped it was correct, and well over a year ago I said we just do not know yet, but trails were on going. Come forward to today and it is no longer a what if, it just doesn't help...
•Statistically significant improvements are seen for mortality, ventilation, ICU admission, hospitalization, recovery, cases, and viral clearance. All remain significant after exclusions. 58 studies from 52 independent teams in 22 different countries show statistically significant improvements in isolation (40 primary outcome, 38 most serious outcome).
•Meta analysis using the most serious outcome shows 62% [51‑70%] and 83% [74‑89%] improvement for early treatment and prophylaxis, with similar results after exclusion based sensitivity analysis, for primary outcomes, for peer-reviewed studies, and for RCTs.
•Results are very robust — in worst case exclusion sensitivity analysis 58 of 92 studies must be excluded to avoid finding statistically significant efficacy.
•No treatment, vaccine, or intervention is 100% effective and available. All practical, effective, and safe means should be used based on risk/benefit analysis. Multiple treatments are typically used in combination, which may be significantly more effective. Only 23% of ivermectin studies show zero events with treatment.
•Over 20 countries adopted ivermectin for COVID-19. The evidence base is much larger and has much lower conflict of interest than typically used to approve drugs.
•All data to reproduce this paper and sources are in the appendix. See [Bryant, Hariyanto, Kory, Lawrie, Nardelli] for other meta analyses with similar results confirming efficacy.