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Medical science has taken the question seriously, however, and found a strong link between schizophrenia symptoms and cannabis use in many large-scale, peer-reviewed studies. Data from four such studies suggest that cannabis use doubles the likelihood of developing a psychotic illness later in life.
But a few small studies have flipped the direction of causation, suggesting that a genetic predisposition to schizophrenia (a disease marked by psychotic episodes such as hallucination) is itself a risk factor for smoking pot. That might explain why pot use is perennially high (pardon the pun) among those diagnosed with schizophrenia.
A European research team led by Kings College, London, suggests that at least part of the reason why schizophrenic symptoms and pot smoking overlap may lie in shared genetic markers. Their study was published online Tuesday in the journal Molecular Psychiatry.
Researchers studied 2,082 people, about 49% of whom reported having smoked pot. They analyzed the participants’ genome, looking for known variations that have been associated with schizophrenia. They found that those with the strongest genetic profile for schizophrenia risk also were more likely to use cannabis, and to use it in greater quantities.
psychcentral.com...
New research from Harvard Medical School, in a comparison between families with a history of schizophrenia and those without, finds little support for marijuana use as a cause of schizophrenia.
Professor John Henry, clinical toxicologist at Imperial College London said research has shown that people with a certain genetic makeup who use the drug face a ten times (1000%) higher risk of schizophrenia. (for example - if your risk of schizophrenia was 6% (due to a family history of mental illness) prior to taking cannabis, it could be 60% -- or more likely than not - after taking cannabis). Every person is different (i.e. has different genes and different environments) - so this "10 Times Higher Risk with cannabis use"- is just a generalization, and it may or may not apply to a given person. The increased risk applies to people who inherit variants of a gene named COMT and who smoked cannabis as teenagers. About a quarter of the population have this genetic make-up and up to 15 per cent of the group are likely to develop psychotic conditions if exposed to the drug early in life. Neither the drug nor the gene raises the risk of psychosis by itself.
Alcohol use disorder (AUD) is the most common co-occurring disorder in people with schizophrenia. Both biological factors and psychosocial factors are thought to contribute to this co-occurrence. Schizophrenia patients with AUD are more likely to have social, legal, and medical problems, compared with other people with schizophrenia. AUD also complicates the course and treatment of schizophrenia.
It's not known what causes schizophrenia, but researchers believe that a combination of genetics and environment contributes to development of the disorder.
originally posted by: wantsome
a reply to: KnightLight
I'm sure the LA Times has no political agenda in legalization now do they? I'll take schizophrenia.com word for it over some biased media outlet.
Cannabis is the most commonly used illicit drug worldwide. With debate surrounding the legalization and control of use, investigating its health risks has become a pressing area of research. One established association is that between cannabis use and schizophrenia, a debilitating psychiatric disorder affecting ~1% of the population over their lifetime. Although considerable evidence implicates cannabis use as a component cause of schizophrenia, it remains unclear whether this is entirely due to cannabis directly raising risk of psychosis, or whether the same genes that increases psychosis risk may also increase risk of cannabis use.
originally posted by: U4ea82
a reply to: KnightLight
I think most people with mental illness do look for a reason. It's only natural to want to find out the cause of something that affects your life so profoundly.
I know what exactly how my illness came about unfortunately I can't go into detail without getting modded because it involves me describing my experience using the drug.
originally posted by: KnightLight
originally posted by: U4ea82
a reply to: KnightLight
I think most people with mental illness do look for a reason. It's only natural to want to find out the cause of something that affects your life so profoundly.
That is what I said. This thread has a Natural Motive. I passed no judgement on that fact.