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A breakthrough in the race to solve antibiotic resistance has been made by scientists. New research reveals an Achilles' heel in the defensive barrier that surrounds drug-resistant bacterial cells. The findings pave the way for a new wave of drugs that kill superbugs by bringing down their defensive walls rather than attacking the bacteria itself. It means that in future, bacteria may not develop drug-resistance at all.
Until now little has been known about exactly how the defensive barrier is built. The new findings reveal how bacterial cells transport the barrier building blocks (called lipopolysaccharides) to the outer surface.
It sounds like it's still hypothetical and I'm very very skeptical. I consider "may not develop drug-resistance at all" to be an extraordinary claim without extraordinary evidence, and the fact they say "may" implies they aren't sure it will happen either.
The findings pave the way for a new wave of drugs that kill superbugs by bringing down their defensive walls rather than attacking the bacteria itself. It means that in future, bacteria may not develop drug-resistance at all.
originally posted by: Arbitrageur
It sounds like it's still hypothetical and I'm very very skeptical. I consider "may not develop drug-resistance at all" to be an extraordinary claim without extraordinary evidence
originally posted by: Necrose
yeah, the fight against bacteria is the fight we are gonna lose.. sooner or later.
originally posted by: Necrose
yeah, the fight against bacteria is the fight we are gonna lose.. sooner or later.
Nope. Viral infections maybe .. bacteria we can already cure every single infection with near zero side effects. The only side effect is the death of all the beneficial bacteria that would need to be repopulated.
originally posted by: Necrose
originally posted by: Necrose
yeah, the fight against bacteria is the fight we are gonna lose.. sooner or later.
Nope. Viral infections maybe .. bacteria we can already cure every single infection with near zero side effects. The only side effect is the death of all the beneficial bacteria that would need to be repopulated.
wrong. wait a second, stop and think:
~Methicillin-resistant Staphylococcus aureus (MRSA)
~Acinetobacter baumannii
~Aspergillis
~Vancomycin-resistant Enterococcus faecium (VRE)
~Pseudomonas aeruginosa
You think you can cure these with ZERO side effects? Don't be silly mate. The drugs of last resort will literally kill your kidneys or anything else. Some of these have mortality over 50%.
Man, you know that Vancomycin in the a "drug of last resort" and when the damn bacteria is resistant to it, you are f..ked up.
"Several of our defensin-mimetic antimicrobial compounds have demonstrated, in pre-clinical research studies, promising activity against fungi such as Candida that can cause infections of the oral cavity," commented Dr. Richard Scott, Vice President of Research at PolyMedix. "Resistance has developed to current treatments used for these infections, creating an important need for a new treatment where resistance is less likely to develop. We believe our small molecule defensin- mimetic compounds represent a novel approach to developing new agents to treat these painful infections which sometimes can be life-threatening, with the important potential advantage of limited opportunity for the development of resistance."
originally posted by: Necrose
a reply to: OccamsRazor04
okay, kill me now but Staphylococcus aureus and various species of Streptococcus are actually LCB. (Lipid-Coated-Bacterium)