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Originally posted by soficrow
Before anyone freaks out - obesity obviously is a very slow form of cancer like most skin cancers - my dad had skin cancer for 50 years, and that's NOT what killed him.
I think that your analogy is simply wrong.
obesity obviously is a very slow form of cancer like most skin cancers -
Cancer from Obesity Can someone develop cancer from obesity? Compelling evidence suggests that yes, obesity causes cancer. However, researchers are still trying to figure out exactly how these two conditions interact.
Obesity statistics show steadily increasing numbers of overweight and obese Americans. The Journal of the American Medical Association (2010) reports that as of 2008, one third of adult Americans were obese. Obesity increases the risk of multiple health conditions, including diabetes, hypertension and cancer.
Developing Cancer from Obesity
The link between cancer and obesity isn't universal. Only certain cancers are associated with obesity. According to the American Cancer Society (2003), obesity increases the risk of:
•Breast cancer (after menopause)
•Colon or rectal cancer
•Gall bladder cancer
•Stomach cancer (in men)
How Obesity Causes Cancer
Exactly how obesity causes cancer is open to debate, although evidence suggests that the cancer's location is just one of the many factors associated with obesity. For instance, obesity affects estrogen levels, perhaps explaining why women can develop uterine cancer from obesity. Obesity also increases the risk of gastroesophageal reflux disease, a known risk factor for esophageal cancer.
Mortality Rates, Cancer and Obesity
Cancer risk factors affect both treatment options and mortality rates. The American Cancer Society (2008) reports that about 14 to 20 percent of cancer deaths in the U.S. can be attributed to excess weight or obesity problems. The report concludes that well over one third of Americans are now overweight, with overweight prevalence more than tripling among adolescents over the past 20 years alone.
Preventing Cancer from Obesity
Since cancer risk increases with obesity, losing weight may lower your risk of obesity-related cancers, among other health benefits. Even a small weight loss can improve health and lower the risk of diabetes or other conditions related to obesity.
While significant research indicates that obesity causes cancer, relatively few studies have determined whether weight loss actually lowers this risk. The increased risk of cancer in the obese suggests that weight loss could reduce cancer risk, but no larger scale clinical trials have explicitly described the relationship between the two.
Originally posted by UltimateSkeptic1
Anything that can be cured by putting your hands in your pockets instead of stuffing Twinkies into your face isn't cancer.
It's a good analogy, but the cell formations/deformations in cancer happen for very different reasons.
Angiogenesis modulates adipogenesis and obesity
Substantial evidence shows that neoplastic and nonneoplastic tissue growth is dependent on angiogenesis. …
Approximately 65% of adults in the United States and more than half of the population in the rest of developed countries are overweight or obese (1). The prevalence in children in all developed countries is about 15% and this number is expected to increase significantly in the near future. Obesity is a complex metabolic disorder that is commonly associated with type 2 diabetes mellitus, hypertension, coronary heart disease, stroke, dyslipidemia, gallbladder disease, hepatic steatosis, sleep apnea, stroke, endometrial disorder, and cancer (2–4). Interestingly, most of these obesity-related disorders are closely associated with vascular dysfunctions. For example, hyper- or hypovascularization could result in onset and progression of diabetic ocular and kidney complications, cardiovascular disease, stroke, and cancer (5–12). Adipose tissue is highly vascularized, and each adipocyte is nourished by an extensive capillary network (13–15). Adipose tissue is considered as the largest endocrine gland because it produces free fatty acids, hormones, growth factors, and cytokines such as leptin, adiponectin, resistin, VEGF, HGF, IGF-1, angiogenin, IL-6, TNF-α, and angiopoietins (Angs). ….
Hyperplasia is a common preneoplastic (pre-cancerous) response to stimulus. Microscopically cells resemble normal cells but are increased in numbers. Sometimes cells may also be increased in size (hypertrophy). Hyperplasia is different from hypertrophy in that the adaptive cell change in hypertrophy is an increase in cell size, whereas hyperplasia involves an increase in the number of cells.
…adipocyte size influences several metabolic functions
(6 –10). …
Among the fourteen genes with markedly higher expression in large compared with small adipocytes, five were classified as immune-related; E-selectin, inter- leukin (IL)-8, SAA, C1q receptor 1, and CXCL2 also known as MIP-2 or macrophage inflammatory protein-2. Components of the metabolic syndrome, such as obesity and type 2 diabetes, are associated with a systemic increase in inflammatory markers (30 –32). ...
…tumor necrosis factor (TNF) has been implicated in both cancer development and progression in some preclinical models. In particular, as a central mediator of inflammation, TNF might represent one of the molecular links between chronic inflammation and the subsequent development of malignant disease. Furthermore, deregulated TNF expression within the tumor microenvironment appears to favor malignant cell tissue invasion, migration and ultimately metastasis formation.
Tumour necrosis factor-alpha (TNFα) is a multifunctional cytokine that has been implicated as mediator of diverse physiologic and pathophysiologic events. These processes include inflammation, cellular survival, growth, differentiation and apoptosis. …
…in addition to mediating inflammation and apoptosis, cytokines play a critical role in the control and maintenance of signalling pathways that regulate mammalian physiology in multiple organ systems. …
It's true that hypertrophy and hyperplasia can be understood as adaptations to environmental influences, but angiogenesis certainly is not
I'd settle for fattnesss is not due to will power, it is certainly a sign something is not right
Can you prove it? Can you provide any evidence to show that "the cell formations/deformations in cancer happen for very different reasons"?