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Originally posted by squiz
reply to post by Barcs
A story on how it may have happened is not scientific fact.
So we have NO known evolutionary pathway.
Sometimes alternative splicing occurs. When this happens the intron is not just removed. Sometimes an exon is also removed or sometimes parts of introns are left in place to be transcribed into messenger RNA. This totally changes the code for the protein, meaning one segment of DNA may actually code for multiple proteins. This vastly increases the complexity of the genome, and brings up a question:
How does the genome decide when to perform alternative splicing and when to do "normal" splicing?
“The amount of DNA in organisms,” Dawkins wrote in 1976, “is more than is strictly necessary for building them: A large fraction of the DNA is never translated into protein. From the point of view of the individual organism this seems paradoxical. If the ‘purpose’ of DNA is to supervise the building of bodies, it is surprising to find a large quantity of DNA which does no such thing. Biologists are racking their brains trying to think what useful task this apparently surplus DNA is doing. But from the point of view of the selfish genes themselves, there is no paradox. The true ‘purpose’ of DNA is to survive, no more and no less. The simplest way to explain the surplus DNA is to suppose that it is a parasite, or at best a harmless but useless passenger, hitching a ride in the survival machines created by the other DNA. “
The discovery of the structure of DNA transformed biology profoundly, catalysing the sequencing of the human genome and engendering a new view of biology as an information science. Two features of DNA structure account for much of its remarkable impact on science: its digital nature and its complementarity, whereby one strand of the helix binds perfectly with its partner. DNA has two types of digital information — the genes that encode proteins, which are the molecular machines of life, and the gene regulatory networks that specify the behaviour of the genes.
Minimal genome should be twice the size, study shows
“Previous attempts to work out the minimal genome have relied on deleting individual genes in order to infer which genes are essential for maintaining life,” said Professor Laurence Hurst from the Department of Biology and Biochemistry at the University of Bath.
“This knock out approach misses the fact that there are alternative genetic routes, or pathways, to the production of the same cellular product.
When you knock out one gene, the genome can compensate by using an alternative gene.
But when you repeat the knock out experiment by deleting the alternative, the genome can revert to the original gene instead.
Using the knock-out approach you could infer that both genes are expendable from the genome because there appears to be no deleterious effect in both experiments.”
Originally posted by uva3021
Certainly doesn't "refute" any scientific views currently held by the over-over-overwhelming majority.edit on 28-6-2012 by uva3021 because: (no reason given)
Information scientists, really? You do realize that information science DOES NOT play a role in genetics & biology, right?
Outside of the field of genetics and microbiology, this shouldn't matter to anybody.
Originally posted by squiz
reply to post by Barcs
The video is not scientific at all. Full of assumptions, stories and simple analogies, skips over some great difficulties etc... A story on how it may have happened is not scientific fact. It also makes the inccorect definition of irreducable complexity and then precedes destroy that eroneous claim. That's a strawman.
It also supports the flagellum with Ken millers TSIII case. Which has been refuted. The TSIII came later. So we have NO known evolutionary pathway. This was the main argument, and it has failed.
Originally posted by squiz
I'm not attacking science at all, I'm all for it. We have good indication that the flagellum motor is IC through genetic knockout test, and no genes switched to preserve function, all 35 knockouts demonstrated a loss of mobility.
Proving that you can't have a functional motor until all the nescesary parts are there. Big surprise!
So I'm just posting this for illucidation and it's very cool too. Forget science for a moment what does your intuition tell you really? If it's random chance, that's fine with me.