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It was only a year ago that ACell’s “miracle powder” was sprinkled on amputated fingers and shown to stimulate the regeneration of fingertips. The world was both awed and skeptical of the powder’s regenerative power, touting that it would revolutionize regenerative medicine or calling it was quack science.
A fingertip is one thing. A thigh, quite another.
Enter Dr. Stephen Badylak, Director of Tissue Engineering at the University of Pittsburg’s McGowan Institute for Regenerative Medicine. Dr. Badylak and colleagues offered Corporal Hernandez an alternative to amputation: regrow the muscle. The key to this seemingly miraculous procedure is a material obtained from pig bladders. As the material’s name, the extracellular matrix implies, it is the mix of chemicals that fills the space surrounding the body’s cells. It’s a complex mixture of hormones, structural proteins, and other molecules that maintain the health and function of the cells, as well as mediates cell-to-cell communication. It also guides tissue growth. Following an intense physical therapy program to strengthen the 30 percent of muscle he had left, doctors made an incision deep into Hernandez’s thigh and applied the extracellular matrix. Instead of a powder like ACell’s, Dr. Badylak’s group turned the material into a gel form. “You can’t use a powder to replace a tendon,” remarked Dr. Badylak. It went to work, spurring not only the growth of muscle tissue but tendons, as he mentioned, and the proper vasculature as well. About six weeks after the surgery the Marine began to feel his strength returning. What’s more, he saw muscle bulking up in the area that the extracellular matrix had been applied. “I used to have a hard time walking and going up and down stairs,” he told Purdue alumnus magazine in a feature story on star alum Dr. Badylak. “I can pretty much walk and do stairs fine now.”
As Dr. Badylak and his colleagues know, every little bit helps. Their ‘MiracleGro For Muscles’ wasn’t always seen as such. Even after years of watching the extracellular matrix successfully morph into whatever tissue it was inserted into–from nerve cells to muscle and bone–the research stubbornly refused to get funded. As Dr. Badylak told the Purdue alumnus, “Nobody thought it was worth funding because it was such a crazy idea. Why would anyone want to put pig tissue in a human?” But profit-minded entrepreneurialism saved the day from pundit-advised conservatism. Eli Lilly and Co. and DuPuy, an orthopedic company in Indiana, put real money into the idea. With the help of drug company coffers Dr. Badylak’s research took off and eventually Washington came aboard. The current study that gave Corporal Hernandez much of his thigh back is a trial in collaboration with the U.S. government. As part of a $70 million government program for regenerative medicine, it’s hoped that Hernandez’s will be the first of many such success stories.
Originally posted by Grey Magic
That doesn't sound Kosher or Halal.
GM
Originally posted by pplrnuts
Originally posted by Grey Magic
That doesn't sound Kosher or Halal.
GM
Who cares about Kosher or Halal or whatever else. This REGROWS body parts. I dont care if nutty folks call it non-kosher or the freakin' anti-christ, it regrows body parts for crying out loud!!!
Who cares if its "Kosher"?
SILLY superstitions!!edit on 16-7-2011 by pplrnuts because: (no reason given)