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Vitamin D receptor ligands have been shown to increase the activity of natural killer cells, and enhance the phagocytic activity of macrophages. Active vitamin D hormone also increases the production of cathelicidin, an antimicrobial peptide that is produced in macrophages triggered by bacteria, viruses, and fungi. Suggestions of a link between vitamin D deficiency and the onset of multiple sclerosis posited that this is due to the immune-response suppression properties of Vitamin D and that vitamin D is required to activate a histocompatibility gene (HLA-DRB1*1501) necessary for differentiating between self and foreign proteins in a subgroup of individuals genetically predisposed to MS. Whether vitamin D supplements during pregnancy can lessen the likelihood of the child developing MS later in life is not known; however, vitamin D fortification has been suggested to have caused a pandemic of allergic disease and an association between vitamin D supplementation in infancy and an increased risk of atopy and allergic rhinitis later in life has been found .
The molecular basis for thinking vitamin D has the potential to prevent cancer lies in its role in a wide range of cellular mechanisms central to the development of cancer. These effects may be mediated through vitamin D receptors expressed in cancer cells. Polymorphisms of the vitamin D receptor (VDR) gene have been associated with an increased risk of breast cancer. Women with mutations in the VDR gene had an increased risk of breast cancer. A 2006 study using data on over 4 million cancer patients from 13 different countries showed a marked increase in some cancer risks in countries with less sun and another metastudy found correlations between vitamin D levels and cancer. The authors suggested that intake of an additional 1,000 international units (IU) (or 25 micrograms) of vitamin D daily reduced an individual's colon cancer risk by 50%, and breast and ovarian cancer risks by 30%. Low levels of vitamin D in serum have been correlated with breast cancer disease progression and bone metastases. However, the vitamin D levels of a population do not depend on the solar irradiance to which they are exposed. Moreover, there are genetic factors involved with cancer incidence and mortality which are more common in northern latitudes. A 2006 study found that taking the U.S. RDA of vitamin D (400 IU per day) cut the risk of pancreatic cancer by 43% in a sample of more than 120,000 people from two long-term health surveys. However, in male smokers a 3-fold increased risk for pancreatic cancer in the highest compared to lowest quintile of serum 25-hydroxyvitamin D concentration has been found.
edit on 30-11-2010 by Corruption Exposed because: fix linkedit on 30-11-2010 by Corruption Exposed because: (no reason given)
Sorry about that, but the rest of MY OP is directly below due to problems with quotations.edit on 30-11-2010 by Corruption Exposed because: problem with quotes
Originally posted by antar
I heard this this am and was astonished that they would make this report about it only being good for bone health when I know that that is a lie.
what is happening is that there are statistics coming in about how this is becoming a miracle healing for many health related problems and so tptb see it as a way of losing money form sickness and RX revenue.
Originally posted by SinkingSun
I used to believe in taking supplements for an advantage in health, but now I have found the exact opposite. Vitamin D, along with other vitamins and minerals, was something I took everyday in quite large doses for not only my health condition but overall health. When I stopped taking any supplements, I actually felt better and realized that my body can not assimilate and utilize these supplements. There are many different forms of all kinds of vitamins and minerals, some definitely working much better than others, but specifically with Vitamin D, I never noticed any improvement in my health. The only Vitamin D supplement you need is sunlight.
Originally posted by SinkingSun
When I stopped taking any supplements, I actually felt better and realized that my body can not assimilate and utilize these supplements.