Oseltamivir was the first orally active neuraminidase inhibitor commercially developed. It is a prodrug, which is hydrolysed hepatically to the active metabolite, the free carboxylate of oseltamivir (GS4071). It was developed by US-based Gilead Sciences and is currently marketed by Hoffmann-La Roche (Roche) under the trade name Tamiflu. In Japan, it is marketed by Chugai Pharmaceutical Co., which is more than 50% owned by Roche. Oseltamivir is generally available by prescription only.
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In January 1997, Donald Rumsfeld, a Board member since 1988, was appointed Chairman of the company.[2] He stood down from the Board in January 2001 when appointed Secretary of Defense at the start of George W. Bush's first term as President. Federal disclosure forms indicate that Rumsfeld owns between USD$5 million and USD$25 million in Gilead stock. The rise in Gilead's share prices from USD$35 to USD$57 per share will have added between USD$2.5 million to USD$15.5 million to Rumsfeld's net worth.[3]
In November 2005, George W. Bush urged Congress to pass $7.1 billion in emergency funding to prepare for the possible bird flu pandemic, of which one billion is solely dedicated to the purchase, and distribution of Tamiflu.
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Wikipedia lists several of the boards of directors of Gilead. One of them is Carla Anderson Hills, a former US Trade Representative in the administration of George H.W. Bush.
An advocate of free trade, she was the primary U.S. negotiator of the North American Free Trade Agreement (NAFTA). On May 28, 1991, Rep. Esteban Torres (D-CA) complained to Hills in a letter that more Hispanics needed to be included in the NAFTA negotiations process.[5] In 2000, Mrs. Hills was awarded the The Mexican Order of the Aztec Eagle (La Orden Mexicana del Aguila Azteca) which is the highest honor conveyed to non-citizens by the Mexican government.
In 2005, Carla Hills participated in [Independent Task Force on North America |The Task Force on the Future of North America] which produced a controversial report called, Building a North American Community sponsored by the Council on Foreign Relations. The general sense was to strengthen trading relationships between the U.S., Canada and Mexico by making trade more efficient, planning for North American infrastructure, fast tracking borders and even some language integration
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Hills is a co-chairman of the CFR, an Executive Committee member of the Trilateral Commission, director of ChevronTexaco, director of AOL Time Warner, and a member of the American International Group. Take a look at the membership of the AIP, which includes George W. Bush, Dick Cheney, Rumsfeld, Richard Perle (in other words, the Bush administration), and people such as Raymond Gilmartinn, who is the CEO of the drug conglomerate Merck.
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