Interesting study about how common cold rhinovirus reduces covid effective growth rate

They have this study that demonstrates people who catch cold very rarely catch covid due to interferon directed against cold. So basically they are saying, if you have cold, you cannot catch covid. If you have covid, then your covid goes away if you catch cold. Something like that. So they modeled how prevalence of cold in the population as a percentage of people having cold controls the effective growth rate Re of covid. Interesting study. Sort of makes sense because from the data we see plateau or slight decline of daily new covid cases between mid September and mid October when more people catch cold in the fall cold peak, and daily new covid cases falls sharply starting in mid April when more people catch cold in the spring cold peak. The model seems to fit the data fairly well.

their study academic.oup.com...


their model in their supplementary analysis model

I was able to find data on prevalence of rhinovirus in Canada's provinces and territories throughout the year, and it appears there are two peaks, one occurring in fall between mid September and mid October, another another peak occurring in spring starting in mid April.

Can adian respiratory virus prevalence within a year


I examined daily new cases data from multiple countries such as France, UK, Czech republic, Hungary, US, Canada all fit this model very well. You can see the trend in the daily new cases, which does not take off until mid October when rhinovirus prevalence starts to decline.

US data

Canada data

France data

Czech data

Hungary data

This is because the innate immune system if primed to fight the common cold viruses. This action is the same as the protection offered from most of the Coronaviruses and some of the Adenoviruses...I have been mentioning this on occasion on posts for many months but don't like making threads.

Having had certain common cold viruses in the past months gives you innate immunity to the coronavirus. There are similarities in most cold viruses so the body can attack them and this results in just a very mild version of the SARS-CoV-2 virus infection. The time of active transmission is low.

This is a wimpy virus for the majority of people and lots of common antiviral foods and herbs limit the replication of the virus or destroy it's enzymes it uses to gain access to the cells.

For some strange reason that I have not found the reason for, they have had zero success with making a vaccine for coronaviruses. It isn't for the lack of trying, they have been trying to make vaccines for the common colds for a long time now with no luck at all.

Notice that the vaccines target the spike protein and not the Coronavirus itself....there is a reason for that. I know about the inability to make a vaccines for common cold viruses but have not found the reasons clearly explained of why they fail miserably. Our bodies know how to fight the common colds, but even those can be dangerous for people who are really old or are immunocompromised because of medicines used to keep rejections of transplants from happening. Certain people with Asthmas also can suffer worse from a common cold. And people who are taking immune system blockers for things like lupus and RA also have increased susceptability to getting colds.

We have a pretty good size risk group in this country, people who have had their lives extended by immune suppression meds are at risk. Some meds used by old people dampen the immune system when they treat a disease took, most meds have side effects, even beta blockers can have a risk of increasing susceptability to catching things...but in this virus, beta blockers may increase your risk of getting sicker from the virus, but they actually might possibly reduce the risk of the virus going covid. As long as they keep the doctors informed with the whole story, they can help you properly if you get a bad case of the virus. Trouble is they are not telling the doctors the whole story, and of course, everyone is different, so what works on some people may not work on others.

They should have just let everyone go out and about and catch a cold. You can't catch a cold if you are locked up under house arrest at home.

And here's the news piece with the lead researcher

a reply to: rickymouse

What they explained was cold causes a fast innate response which enveloped viruses like flu and coronavirus are vulnerable to and which rhinovirus is resistant to. Rhinovirus is simple and does not suppress immune response, whereas flu and coronavirus are complex enveloped viruses which suppress innate immune response. So that's why they showed in the lab if a person has flu or coronavirus, then introducing rhinovirus to that person gets rid of flu or coronavirus due to the innate immune response rhinovirus triggers. They go on to say humans and rhinovirus have over the eons evolved a symbiotic relationship, whereby rhinovirus protects humans from potentially lethal viruses such as flu and coronavirus and humans allow rhinovirus to infect from time to time (hence called common cold) with very mild symptoms and no damage to tissue. Interesting stuff.

originally posted by: rickymouse
They should have just let everyone go out and about and catch a cold. You can't catch a cold if you are locked up under house arrest at home.

Indeed, the unusually high prevalence of rhinovirus in the US this summer after lifting mask mandate caused covid cases to fall sharply.

news 1

news 2

And as you can see daily new covid cases in the US dropped to very low in the summer as a result.

data

originally posted by: rickymouse
They should have just let everyone go out and about and catch a cold. You can't catch a cold if you are locked up under house arrest at home.

LOLs if everyone catches a cold covid-19 be extinct within days. They don't want that. They want to keep it around to sell more money and earn more profit.

A while back there was a lot of talk about Interferon, which was a hypothetical substance created by cells that work in such a way that we can really only catch one viral infection at a time. It was thought that by stimulating Interferon production we could block most viruses. I don't think it ever really worked out. Interesting theory, though.

originally posted by: Blue Shift
A while back there was a lot of talk about Interferon, which was a hypothetical substance created by cells that work in such a way that we can really only catch one viral infection at a time. It was thought that by stimulating Interferon production we could block most viruses. I don't think it ever really worked out. Interesting theory, though.

Administering interferon as a drug is expensive. However, if you can make a puffer containing rhinovirus, it's really cheap. Say you store a puffer in the fridge, it's good for a year at least. Suppose before you go to a party where it's risky to get flu or covid, you can give yourself a puff, and you are protected for the next week or so. Even if you give yourself a puff every week, a puffer should be good for a whole year. It's cheaper than a flu shot or a covid vaccine, and you don't even need a jab which can cause a sore arm. A dose from a puffer should also be low enough that you don't get any cold symptoms (indeed, some 60% of cold don't produce any symptoms) while generating sufficient interferon response to protect you from flu and covid for the next whole week. Now that's a bang for the buck, and also good for people who hate needles.