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I also know that nearly 100% of the US population is infected by this disease, called fibromuscular dysplasia (FMD).
Originally posted by Ghaleon4
Fibromuscular dysplasia (FMD) is an arterial disease of unknown etiology typically affecting the medium and large arteries of young to middle-aged women.
References:
* “The occurrence of fibromuscular dysplasia in the arteries of domestic turkeys.” Julian LM. Am J Pathol. 1980 Nov;101(2):415-24. PMID: 7435545
* “The ultrastructure of spontaneous coronary arterial lesions in steelhead trout (Salmo gairdneri).” House EW, Benditt EP. Am J Pathol. 1981 Sep;104(3):250-7. PMID: 7294154
* “Fibromuscular dysplasia in intramuscular arteries of Japanese quail (Coturnix coturnix japonica).” Braga IS 3rd, Tanaka S, Itakura C, Mizutani M. J Comp Pathol. 1996 Feb;114(2):123-30. PMID: 8920213
* “All forms of fibromuscular dysplasia are progressive and have variable rates of progression.”
Radiology, Vol 139, 45-51, Copyright © 1981 by Radiological Society of North America. Progression of renal artery fibromuscular dysplasia in 42 patients as seen on angiography. V Goncharenko, AJ Gerlock Jr, MI Shaff and JW Hollifield. radiology.rsnajnls.org...
* “Fibromuscular dysplasia is a chronic progressive disease and some cases progress rapidly in a few months.”
Angiology. 1999 Feb;50(2):153-6. Fibromuscular dysplasia involving coronary arteries--a case report. Ogawa T, Nomura A, Komatsu H, Fujii S, Urasawa K, Okamoto H, Kitabatake A. Department of Cardiovascular Medicine, Hokkaido University School of Medicine, Sapporo, Japan. PMID: 10063947
* “Age and fibroplasia as preconditions for atheronecrosis in human coronary arteries.” Arch Pathol Lab Med 1987 Oct;111 (10):957-63 Tracy RE, Kissling GE. PMID: 3632271
* “Evolution and progression of atherosclerotic lesions in coronary arteries of children and young adults.” Arteriosclerosis. 1989 Jan-Feb;9(1 Suppl):I19-32 Stary HC. Louisiana State University, School of Medicine, New Orleans 70112. PMID: 2912430
For an explanation of how it works, see:
* “Regulatory function of the bone marrow in immunogenesis. II. The stimulating effect of a humoral marrow factor on antibody production in vitro and in vivo.” Dev Comp Immunol. 1979 Fall;3(4):697-707. Petrov RV, Mikhailova AA, Zakharova LA, Stepanenko RN. PMID: 527748
NOTE: Hormones trigger FMD, which causes vasospasms that interrupt blood flow to bone marrow, which interferes with the immune system and antibody production. …So if you want to know how FMD causes PMS and post-partum depression or psychosis for example, start by studying the mechanics: vasospasm to bone marrow to immune system.
Originally posted by Ghaleon4
Now...with that said...what on earth are you talking about?
* NEWSFLASH: 1989. “Fibromuscular dysplasia may be a systemic disease…, and may affect the central nervous system.”
Renovascular hypertension and demyelimating disease in a young woman. Alaska Med 1989 Jul-Dec;31(4):137-43. Neubauer RL. PMID: 2596648
* “Focal fibromuscular dysplasia of small coronary arteries is not so rare as it is unrecognized.”
Morphologic characteristics and functional significance of focal fibromuscular dysplasia of small coronary arteries. Am J Cardiol. 1990 Apr 3;65(14):12G-22G. James TN. World Health Organization Cardiovascular Center, Galveston, Texas. PMID: 2181850
* The causes of death in patients with carotid FMD were heart attack (44.4%), cancer (33.3%) and stroke (22.2%) – now the three leading causes of death in the USA, in that order.
Fibromuscular dysplasia of the internal carotid artery: long-term surgical results. J Cardiovasc Surg (Torino). 1993 Dec;34(6):465-72. Moreau P, Albat B, Thevenet A. Service de Chirurgie Thoracique et Cardio-Vasculaire, Centre Hospitalier Universitaire, Montpellier, France. PMID: 8300709
* “Trends for mortality from heart disease, stroke, lung cancer, and, less distinctly, cancer other than lung cancer, tend to be similar in different countries, ... suggesting the existence of common causes amenable to the same preventive measures.”
Circulation. 1994 Jul;90(1):574-82. Heart disease, cancer, and stroke mortality trends and their interrelations. An international perspective. Thom TJ, Epstein FH. Epidemiology and Biometry Program, National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Md. PMID: 8026045
circ.ahajournals.org...;90/1/574
www.emedicine.com...
“FMD frequency in the USA: incidence of new cases in adults diagnosed by angiography – 0.6%; diagnosed in autopsy – 1.1%.”
NOTE: Incidence means new cases found yearly, presented as a % of the total population.
Also see Puri, PMID: 10334397.
* “Fibromuscular dysplasia in a child: a generalized arterial disease.” Acta Paediatr Scand 1980 Jul;69(4):563-6. Pesonen E, Koskimies O, Rapola J, Jaakelainen J. PMID: 7446106
* “This report suggests that FMD should be considered to be a systemic angiopathy…”
“Clinical significance of cerebral aneurysm in renovascular hypertension due to fibromuscular dysplasia: two cases in siblings.” Angiology 1989 Jun;40 (6):581-8. Ouchi Y, Tagawa H, Yamakado M, Takanashi R, Tanaka S. Department of Internal Medicine, Mitsui Memorial Hospital, Tokyo, Japan. PMID: 2719343
See above, and more:
* First official acknowledgement:
Hypertension in unilateral renal disease. J Urol 1938, 39:611-626. Leadbetter WF.
* “The presence of such intimal lesions suggests that there was a systemic factor that caused the formation of recurrent thrombi in the systemic vessels in these patients. These cases are the first ones reported in which an association between FMD and pulmonary hypertension has been observed. The pathogenesis of the thrombi in our patients was thought to be recurrent pulmonary thromboembolisms resulting from FMD.”
“Thromboembolic pulmonary hypertension due to disseminated fibromuscular dysplasia.” Pediatr Cardiol 1996 Sep-Oct;17(5):340-5. Fukuhara H, Kitayama H, Yokoyama T, Shirotani H. Division of Pediatric Cardiology, Kinki University School of Medicine, 377-2, Ohno-Higashi, Osaka-Sayama, Osaka 589, Japan. PMID: 8660454
* “A case of multivessel fibromuscular dysplasia involving the cervico-cephalic arteries, the right renal artery and the iliac arteries is reported. It was associated with reversible bilateral internal carotid arteries and vertebral arteries dissection, left thalamic infarct, right hemorrhagic cerebellar infarct, renovascular hypertension and intermittent claudication of the right lower limb. This report indicates that fibromuscular dysplasia is a systemic angiopathy.”
“Fibromuscular dysplasia. A case report with multivessel vascular involvement.” Int Angiol 1994 Dec;13(4):347-50. Fisicaro M, Tonizzo M, Pozzi Mucelli R, Pincetti E, Casagrande S, Carraro N, Bussani R. Department of Internal Medicine, University of Trieste, Italy. PMID: 7790759
Originally posted by Ghaleon4
When I asked "What are you talking about", I was specifically wondering how FMD applies to the abuse of children?
Originally posted by AlwaysLearning
IMHO, capita punishment doesn't appear to be a deterrent to murder in the U.S., so why would it be a deterrent to child abuse???