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A drug that could stop multiple sclerosis in its tracks has been discovered by scientists. In a major breakthrough in the battle against the devastating disease, researchers have pinpointed the chemical “driving force” behind MS. Without it, the disease does not develop. And when it is mopped up, symptoms are greatly eased, even in brains already ravaged by the illness. The results come from experiments on mice but the researchers say they are “quietly optimistic” that taking the same tack will help people with MS. The first trials on patients are pencilled in for later this year.
The excitement centres on two studies published recently which show an immune system chemical called GM-CSF to be the “vital piece in the jigsaw” of MS.
Mopping up excess GM-CSF may also help treat other conditions, including diabetes, it is hoped.
The drug was also given to mice whose disease was similar to the most common form of MS, in which relapses are followed by periods of remission. Here, mopping up the GM-CSF prevented any further relapses, the journal Nature Immunology reports.
Becher said: “We are extremely hopeful but whether this form of therapy will actually help MS patients remains to be seen. Quiet optimism is the way to go.
“I am not sure this is going to work in patients but, based on the mouse data, I believe GM-CSF is a good thing to target.”
Originally posted by Matti420
reply to post by iforget
As seen where? I dont see "said subject" being mentioned anywhere in that article...
I dont supose it really matters as either way this is a potentially awesome medical find.
Multiple sclerosis (abbreviated MS, also known as disseminated sclerosis or encephalomyelitis disseminata) is an inflammatory disease in which the fatty myelin sheaths around the axons of the brain and spinal cord are damaged, leading to demyelination and scarring as well as a broad spectrum of signs and symptoms.
MS affects the ability of nerve cells in the brain and spinal cord to communicate with each other.
Almost any neurological symptom can appear with the disease, and often progresses to physical and cognitive disability.
The drug was also given to mice whose disease was similar to the most common form of MS
And when it is mopped up, symptoms are greatly eased
Originally posted by iforget
A drug that could stop multiple sclerosis in its tracks has been discovered by scientists. In a major breakthrough in the battle against the devastating disease, researchers have pinpointed the chemical “driving force” behind MS. Without it, the disease does not develop. And when it is mopped up, symptoms are greatly eased, even in brains already ravaged by the illness. The results come from experiments on mice but the researchers say they are “quietly optimistic” that taking the same tack will help people with MS. The first trials on patients are pencilled in for later this year.
source
wow just to awesome a hope for me to comment Let's all hope the promising results carry over in the human trials.