posted on Feb, 16 2012 @ 08:40 AM
For those of you who unaware of what Celiac or Coeliac disease (as it’s known to our UK members) Wikipedia offers the following description.
Source - Wikipedia page
an autoimmune disorder of the small intestine that occurs in genetically predisposed people of all ages from middle infancy onward. Symptoms
include chronic diarrhoea, failure to thrive (in children), and fatigue, but these may be absent, and symptoms in other organ systems have been
Below are two pictures, one is a normal intestine the other is one from a celiac sufferer. You can clearly see the difference. The Celiac endo shows
scalloping of the folds and cracked-mud appearance of the mucosa. (Quote from the picture)
Normal Endo source
Celiac Endo source
In a nutshell those people who are diagnosed with this disease must adhere to a strict diet. One that removes all traces of wheat; i.e. breads and
cereals but those are the obvious ones. You would be surprised how prevalent wheat is in our daily diets. Wheat can be found in medications, used for
flavouring and used during the production of processed foods.
Living with 2 confirmed celiac sufferers it has been quite a chore. Not to mention expensive. Gluten free products are typically 20% more expensive
than the gluten alternative.
I read a recent article in readers digest (March 2012 edition) about a possible vaccine. Australian scientists have stumbled upon a peptide that when
administered to Celiacs sufferers will retrain the body to accept and process gluten. According to the article, a vaccine could be available as early
I must apologize, i have thus far failed to locate an online version of the article but I will provide a link to the biotech company who has picked up
ImmusanT, according to their website is an American company located in Cambridge, MA. They have raised $20 Million to fund their research. They
product they are developing is called Nexvax2 which is based on Peptide-based immunotherapy.
What is Peptide-based immunotherapy? Article here.
Nexvax2 will be administered in small frequent doses over two months and this would reprogram the body's response to gluten, this according to the
readers digest article.
While I am doubtful that it will outright cure celiac, I do hope that it helps reduce the severity of a gluten attack.
Wikipedia page for Celiac desease
Normal Endo source picture
Celiac Endo source picture
Peptide-based immunotherapy Article.