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The cortex is a part of the brain that plays a key role in memory, attention, awareness, thought, language and consciousness. While it is well-known that defects in this region are associated with schizophrenia, it is not understood how these defects develop.
“These processes are critical for normal brain function. However, as these new results show that DISC1 is a protein whose function can be dynamically regulated, it opens up the possibility of pharmaceutical and biotech companies designing new medicines able to correct defects in DISC1 that lead to the debilitating disease of schizophrenia.