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We try to cross the H1N1 virus and H5N1 influenza Lyon
18.03.2010 04: 00 p.m.
In the P4, a laboratory for maximum security, current experience strives to determine the conditions of hybridization of two viruses. The first spreads quickly but kills little, the second is not contagious, but often fatal
Since three weeks, the Lyon P4 suspended all its other manipulations. This laboratory maximum security - there is that one in France and 20 in the world - currently focuses on high-risk experience: attempting to cross between the new H1N1 virus and the avian influenza, the H5N1. The first spreads much and kills little, the second low spreads and kills many. A hybridization of both would be calamiteuse.
"We are trying to understand, that infects a cell with these two virus, what genetic determinants which would enable them to exchange their genes (especially among the ED. pig)" summarizes the Lina, Bruno virologue, who heads A flu for the Inserm laboratory work. Three staff biologists have been seconded to perform these tests agreed and endorsed at the ministerial level. They are provided with specific passports, assisted by half a dozen engineers attached to the site. "All manipulations are diving and obey very binding regulations" provides Bruno Lina.
If experience is well linked to national influenza virus reference centre that it directs, its purpose wouldn't, would lead to a vaccine, but fair "cognitive": "why to produce a vaccine against a virus that doesn't exist?". Or not yet. The first results will not fall before two months and decide of the follow-up to this operation (provisional) budget of 200,000 euros. Currently, "has been a few tests, but it did of the very preliminary results" continues the virologue. If it is too early to suggest anything about the likelihood of the emergence of a such Monster viral, "today the risk seems low" entrusted. And concluded: "it's good news.
H1N1: pending the second wave
If media seem now to have finished with the influenza A, is not without doubt our agencies. "It is a certainty, it will be well a new epidemic wave" think Bruno Lina, Director of the national reference of influenza viruses. "The H1N1 virus becomes a seasonal virus and this epidemic will then have a moderate impact either it triggers a second wave next winter" continues. Second wave that may impact more important, as has been the case during epidemics grippales winters of 1957 (H2N2) and 1968 (H3N2): "this is when the second wave, 58 winter and winter 69, there had been more deaths" recalls the virologue. Same "if anything makes sense with the flu, it must still bear it in mind. Without being alarmist, the researcher also keeps an eye on the H5N1 avian (287 death on 486 cases worldwide) who finds, "seems a little resume of the hair of the beast". As evidenced by five new cases listed in Egypt.
O.S. - Ebola and Marburg - Les 4 type arénavirus filovirus: Lassa virus of African origin and the arénavirus of South American origin. -Crimean - pox virus - Congo haemorrhagic fever, the Henipavirus Hendra - influenza virus and Nipah virus A H5N1 original