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originally posted by: RAY1990
a reply to: tanstaafl
They have a legal charter to hunt Beluga whales that are saturated in vitamin D. There's other cultures in similar climates that don't have such access. That was mostly my point.
Mostly supplemented by synthesized vit d these days.
I don't believe humans need vitamins in the numbers you suggest.
Don't believe humans must sunbathe as much as you say to be healthy.
Studies have shown that deficiency in LL-37 in humans leads to an increased susceptibility to infection , and mice deficient in the murine cathelicidin (mCRAMP) also display an increased susceptibility to both bacterial and viral infections of the airway tract, skin, urinary tract and gut [74,75,76]. On the contrary, exogenous delivery of LL-37 in murine models offered enhanced clearance and reduced mortality in lethal influenza infection .
Vitamin D is known for its positive effects on bone mineralization and calcium metabolism, and severe deficiency has classically been linked to rickets. Mounting evidence now points to a key immunomodulatory role for vitamin D and to a link between vitamin D deficiency and increased susceptibility to acute viral infections . Furthermore, despite conflicting reports and heterogeneity within studies, a recent systematic review encompassing 10933 participants in 25 randomized controlled trials concluded that vitamin D supplementation reduced the risk of acute respiratory infection, with stronger protective effects in patients with baseline 25-hydroxyvitamin D levels