posted on Oct, 5 2019 @ 09:14 PM
This is an awesome technological application of carbon nanotubules within biomedical engineering, which I thought I'd share as it really ticked the
boxes in terms of my science interests.
Dr Andy Tay at the National University of Singapore has developed a novel 'transfection' methodology for the transfer of modified DNA sections into a
patient's immune cells, in essence sending them whooshing through carbon nanotubules which are set up akin the cell membrane & then electrically
stimulated in a targeted manner, to increase porosity of the cell membranes, allowing for easier transit of the DNA sections into each cell. I say
'whooshing' because the electrostatic forces applied to the carbon nanotubules to increase cell membrane porosity also have the effect of sucking the
DNA through the nanotubule, like a bullet down a rifled barrel, in a manner of speaking.
ETA - The field of operations is immunotherapy for cancer-fighting purposes at this stage.
This technology is patented & licensed to a start-up in the USA, and is called NANO-ELECTRO-INJECTION, and I think we'll be hearing of many more of
its applicable uses in biomedical sciences in the near future. There are several efficiency benefits to the use of this technique over & above
existing techniques for DNA transfection, which you can read about in the article! Enjoy...
NUS scientist designs 'express courier service' for immune cells
Spoiler - he's now working on a version of this technique which also applies the use of magnets. I like the way he thinks!
edit on OctoberSaturday19110CDT09America/Chicago-050016 by FlyInTheOintment because: per ETA