It looks like you're using an Ad Blocker.

Please white-list or disable AboveTopSecret.com in your ad-blocking tool.

Thank you.

 

Some features of ATS will be disabled while you continue to use an ad-blocker.

 

Cystic fibrosis patients may benefit from repurposed approved drug

page: 1
3

log in

join
share:

posted on Jun, 4 2016 @ 11:20 PM
link   
MNT: Medical News Today (MNT) is owned and operated by MediLexicon International Ltd, a leading healthcare internet publishing company, with headquarters in the United Kingdom and offices in Taiwan.

Written by Catharine Paddock PhD
Published: Friday 3 June 2016
.
www.medicalnewstoday.com...
.



New research suggests that a drug already approved for the treatment of metabolic acidosis - where the body has too much acid - could be repurposed and used to treat airway disease in patients with cystic fibrosis. The drug showed enhanced ability to kill bacteria in the airways of pigs and mucus samples from human patients with cystic fibrosis.
.
. . .
.
The mucus build-up is a result of a problem with transporting ions in and out of cells, which causes the affected tissue surfaces to become too acidic.
.
In the lungs, if the airway surface liquid (ASL) becomes too acidic, it is less able to defend against bacteria and other pathogens.
.
. . .
.
"We found that Tham aerosols increased ASL pH in vivo for at least 2 hours and enhanced bacterial killing," note the authors.

.
THIS really sounds like it could improve the quality of life of CF patients.
.
Gads what a horrid disease.
.
I hope ATSers with loved ones or their own CF problems will investigate this and see if it's fitting for application in their cases.
.
It sounds like there should be no delay in getting such treatment given that it's with a known drug already etc.
.
What do ATSers around such CF patients think?
.
May such help lengthen and improve the lives of those with CF.
.




new topics
 
3

log in

join