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Most of the injuries reported involved dogs and cats that had been hurt as they attempted to escape from their cages.
Another major cause of death was underlying health conditions, such as dogs with short or snub noses, which were then aggravated by the stress of travelling.
Several airlines are currently reviewing their policies for those types of animals, such as pugs and English bulldogs.
These brachycephalic breeds, more frequently than others, experience breathing problems when faced with stressful conditions.
Thus, they have a particularly high risk of suffocating in-flight.
Despite friendly staff and smooth air, animals travelling in the cargo hold of a commercial jet do face their fair share of environmental stresses, such as varying temperatures, loud noises and air pressure drops.
In 2011, 35 pets died while travelling on U.S. airlines and in 2012, 29 pets died.
Between 2010 and 2013, it was Delta reported the greatest number of animal incidents and was held responsible for 41 of the 97 reported deaths.
However, Delta maintains that the reason for their higher numbers is simply because they carry more pets than any other competing airline.
Humane Society Travel Tips for your pet