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"How does chronic wasting disease (CWD) in deer and elk spread from animal to animal? … University of Wisconsin-Madison researchers show that prions - infectious proteins considered to be at the root of the disease - literally stick to some soil types, suggesting that the landscape may serve as an environmental reservoir for the disease."
* Prion transmission in blood and urine: what are the implications for recombinant and urinary-derived gonadotrophins? Hum Reprod. 2002 Oct;17(10):2501-8. Reichl H, Balen A, Jansen CA. PMID: 12351519
"This finding indicates that previous attempts to quantify BSE and scrapie prions in milk or non-neural tissues, such as muscle, may have underestimated infectious titers by as much as a factor of 10,000, raising the possibility that prions could be present in these products in sufficient quantities to pose risk to humans..."
* UCSF-Led Team Reports New Test Improves Detection of Prions in Animals
"It is possible that infectious prions have leached into the water supply, government scientists admit. … The main risks to human health are contamination of water supplies from buried animals, or carcasses awaiting disposal, and pollution of the air from burning pyres."
"Fly larvae and mites were exposed to brain-infected material and were readily able to transmit scrapie (prions) to hamsters. New lines of evidence have confirmed that adult flies are also able to express prion proteins. Several cell types found on the human skin, including keratinocytes, fibroblasts and lymphocytes, are susceptible to the abnormal infective isoform of the prion protein, which transforms the skin to produce a potential target for prion infection."
* Could ectoparasites act as vectors for prion diseases? Int J Dermatol. 2003 Jun;42(6):425-9. Lupi O. Center for Vaccine Development, University of Texas Medical Branch at Galveston, Galveston, TX, USA. PMID: 12786866
This 1986 paper describes how "proteinaceous capsids" use viruses as vehicles of transmission, and how the subsequent RNA interference silences genes.
* "Viral influences on aflatoxin formation by Aspergillus flavus." Appl Microbiol Biotechnol 24:248-252. Schmidt FR, Lemke PA, Esser K (1986)
"Epidemiological observations indicate that a microbial vector is responsible for the transmission of natural prion disease in sheep and goats … A similar phenomenon was already described with a protein antigen of the ameba Naegleria gruberi. ...It is proposed that many microbial proteins may be capable of replicating themselves in mammalian cells eliciting and sustaining thereby degenerative and/or autoimmune reactions subsequent to infections with microorganisms."
* Med Hypotheses. 1999 Aug;53(2):91-102. Is the pathogen of prion disease a microbial protein? Fuzi M. Budapest Institute of National Public Health and Medical Officer Service, Hungary. PMID: 10532698
"Although composting reaches high enough temperatures for a long enough time to kill most pathogens ...it would be highly unlikely that composting would inactivate prions."
Originally posted by grimreaper797
very disturbing. think about if masquitoes (sp?) could spread such a thing....that would be bad bad news. this is bad news as it is because of the careless eating habits of people....very disturbing stuff here.
Originally posted by LazarusTheLong
Give us some hope here soficrow...
Long way off for human prion infections, but it shows hope...