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THERAPEUTIC ADVANCE
Review of the Emerging Evidence Demonstrating the Efficacy of Ivermectin in the Prophylaxis and Treatment of COVID-19
Kory, Pierre MD1,*; Meduri, Gianfranco Umberto MD2; Varon, Joseph MD3; Iglesias, Jose DO4; Marik, Paul E. MD5Author Information
American Journal of Therapeutics: May Jun 2021 - Volume 28 - Issue 3 - p e299-e318
doi: 10.1097/MJT.0000000000001377
originally posted by: angelchemuel
a reply to: anonentity
Thank you. I'll just keep puffing then
Rainbows
Jane
originally posted by: TheAMEDDDoc
It’s an interesting virus, learn more every day lol.
April 30, 2021
The novel coronavirus’ spike protein plays additional key role in illness
Salk researchers and collaborators show how the protein damages cells, confirming COVID-19 as a primarily vascular disease
LA JOLLA—Scientists have known for a while that SARS-CoV-2’s distinctive “spike” proteins help the virus infect its host by latching on to healthy cells. Now, a major new study shows that the virus spike proteins (which behave very differently than those safely encoded by vaccines) also play a key role in the disease itself.
The paper, published on April 30, 2021, in Circulation Research, also shows conclusively that COVID-19 is a vascular disease, demonstrating exactly how the SARS-CoV-2 virus damages and attacks the vascular system on a cellular level. The findings help explain COVID-19’s wide variety of seemingly unconnected complications, and could open the door for new research into more effective therapies.
“A lot of people think of it as a respiratory disease, but it’s really a vascular disease,” says Assistant Research Professor Uri Manor, who is co-senior author of the study. “That could explain why some people have strokes, and why some people have issues in other parts of the body. The commonality between them is that they all have vascular underpinnings.”
Rajendra Kapila, US- based world renowned infectious diseases expert, has died of Covid-19 in India. He was aged 81. Kapila, who had traveled to India to take care of his family, was supposed to return to the US in the second week of April but had to be hospitalized in Delhi after testing positive for the virus
However, the intriguing thing about the death of the University of Rutgers Professor who had practised medicine in the United States for 50 years and known for his extensive work on HIV/AIDS is that he and his wife Dr Deepti Saxena Kapila, had taken both doses of the Pfizer vaccine prior to his arrival in India........
...However, according to what Tao Lina, a Shanghai-based vaccine expert, told the Global Times on Wednesday there is no direct evidence showing whether the Pfizer vaccine is effective on this variant or not, while noting that China-developed inactivated vaccines might be more effective against the double mutant than mRNA ones.
“Technically, Pfizer vaccine uses human cells to synthesize S protein in the human body to produce antibodies, whereas China-developed vaccines, including Sinovac and Sinopharm, use inactivated viruses as antibodies, which may cover more variants than Pfizer does,” Tao said.
Tao added that while the efficacy of Pfizer against the new double mutant remains unknown, previous medical studies suggested a reduced efficacy rate of Pfizer shots against other Covid-19 variants.
“The human body develops resistance to vaccines, and the variants may need even five or six doses of vaccine instead of merely two to produce enough protection,” he noted.
Still, according to a press release on its official website, Pfizer said its vaccines show a 95.3 percent efficacy rate against severe COVID-19 cases, which has been defined by the US Food and Drug Administration.
In my family, we have a rule: If you consider having an experimental medical procedure done,
Don’t even think of insisting that anyone else have it done, inside or outside the family, because they control their own bodies and health decisions, not you; and Be sure you have read about and can explain in your own words all of the known risks of that procedure before embarking on it. Also, consider potential future risks.
I ask that you, the reader, at least take time to consider the above, and at least consider reading information in the links below, before submitting to this experimental medical procedure.......
Statement of interests
The author has served as an expert witness in court cases involving questions of safety regarding vaccines.