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A time-lapsed video reveals how bacteria develop resistance to increasingly higher doses of antibiotics in a matter of days.
The experiments, described in the Sept. 9 issue of Science, are thought to provide the first large-scale glimpse of the maneuvers of bacteria as they encounter increasingly higher doses of antibiotics and adapt to survive—and thrive—in them.
The invention was borne out of pedagogical necessity—to teach evolution in a visually captivating way to students in a graduate course at HMS.
Source
Journal article for you-know-who
In the span of 10 days, bacteria produced mutant strains capable of surviving a dose of the antibiotic trimethoprim 1,000 times higher than the one that killed their progenitors. When researchers used another antibiotic—ciprofloxacin—bacteria developed 100,000-fold resistance to the initial dose.
A time-lapsed video reveals how bacteria develop resistance to increasingly higher doses of antibiotics in a matter of days.
originally posted by: testingtesting
a reply to: trollz
Well that was cool. I expect the usual lot in bleating that it isn't a goat turning into a tortoise or something so it isn't evolution. Just ignore those.
originally posted by: intrptr
a reply to: trollz
A time-lapsed video reveals how bacteria develop resistance to increasingly higher doses of antibiotics in a matter of days.
Thats adaptation, not 'evolution', right?
The survivors that were immune multiply, this is how super strains 'develop'. The same thing happens when farmers spray insecticide on their crops. The survivors procreate, then a new more potent insecticide is sprayed and the survivors again , multiply. Eventually our insecticides and antibiotics aren't going to work anymore.
originally posted by: testingtesting
a reply to: trollz
We have seen Evolution in action a few times I will add to the thread after work.
originally posted by: trollz
originally posted by: intrptr
a reply to: trollz
A time-lapsed video reveals how bacteria develop resistance to increasingly higher doses of antibiotics in a matter of days.
Thats adaptation, not 'evolution', right?
The survivors that were immune multiply, this is how super strains 'develop'. The same thing happens when farmers spray insecticide on their crops. The survivors procreate, then a new more potent insecticide is sprayed and the survivors again , multiply. Eventually our insecticides and antibiotics aren't going to work anymore.
As I understand, mutant bacteria were created which reproduced and spread, ultimately creating bacteria that were different from the earliest bacteria. So... It's not just one kind of bacteria adapting, it's one kind of bacteria evolving into new strains of bacteria that are different from the originals in order to survive.
originally posted by: Teikiatsu
originally posted by: trollz
originally posted by: intrptr
a reply to: trollz
A time-lapsed video reveals how bacteria develop resistance to increasingly higher doses of antibiotics in a matter of days.
Thats adaptation, not 'evolution', right?
The survivors that were immune multiply, this is how super strains 'develop'. The same thing happens when farmers spray insecticide on their crops. The survivors procreate, then a new more potent insecticide is sprayed and the survivors again , multiply. Eventually our insecticides and antibiotics aren't going to work anymore.
As I understand, mutant bacteria were created which reproduced and spread, ultimately creating bacteria that were different from the earliest bacteria. So... It's not just one kind of bacteria adapting, it's one kind of bacteria evolving into new strains of bacteria that are different from the originals in order to survive.
The bacteria in the highest antibiotic zone are the same as the bacteria that they started with. No fundamental change was made to their genetics.
Their metabolism is the same, their membrane markers are the same, etc. They can still be identified by their metabolisms, stains, etc.
They did not become anything new.
At most they are a different strain of the same organism.
As I have heard before, 'survival of the fittest' is not the same as 'arrival of the fittest.'
originally posted by: Teikiatsu
a reply to: peter vlar
Read their papers and point out where any new genetic information was created, instead of transduction.
I'm patient. I'll wait.
Here, we introduce an experimental device, the microbial evolution and growth arena (MEGA)–plate, in which bacteria spread and evolved on a large antibiotic landscape (120 × 60 centimeters) that allowed visual observation of mutation and selection in a migrating bacterial front. While resistance increased consistently, multiple coexisting lineages diversified both phenotypically and genotypically. Analyzing mutants at and behind the propagating front, we found that evolution is not always led by the most resistant mutants; highly resistant mutants may be trapped behind more sensitive lineages.