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Furthermore, compounds found in cannabis have been shown to kill numerous cancer types including: lung cancer [9], breast and prostate [10], leukemia and lymphoma [11], glioma [12], skin cancer [13], and pheochromocytoma [14]. The effects of cannabinoids are complex and sometimes contradicting, often exhibiting biphasic responses. For example, in contrast to the tumor killing properties mentioned above, low doses of THC may stimulate the growth of lung cancer cells in vitro [15].
In conclusion, while both tobacco and cannabis smoke have similar properties chemically, their pharmacological activities differ greatly. Components of cannabis smoke minimize some carcinogenic pathways whereas tobacco smoke enhances some. Both types of smoke contain carcinogens and particulate matter that promotes inflammatory immune responses that may enhance the carcinogenic effects of the smoke. However, cannabis typically down-regulates immunologically-generated free radical production by promoting a Th2 immune cytokine profile. Furthermore, THC inhibits the enzyme necessary to activate some of the carcinogens found in smoke. In contrast, tobacco smoke increases the likelihood of carcinogenesis by overcoming normal cellular checkpoint protective mechanisms through the activity of respiratory epithelial cell nicotine receptors. Cannabinoids receptors have not been reported in respiratory epithelial cells (in skin they prevent cancer), and hence the DNA damage checkpoint mechanism should remain intact after prolonged cannabis exposure. Furthermore, nicotine promotes tumor angiogenesis whereas cannabis inhibits it. It is possible that as the cannabis-consuming population ages, the long-term consequences of smoking cannabis may become more similar to what is observed with tobacco. However, current knowledge does not suggest that cannabis smoke will have a carcinogenic potential comparable to that resulting from exposure to tobacco smoke.
originally posted by: Shakawkaw
originally posted by: GoShredAK
I have zero reason not to believe marijuana smoke is actually harmless to the lungs.
Unfortunately, it's not really about what you believe. We need further study. Until then, I've got my g-pen.
originally posted by: Sremmos80
a reply to: Shakawkaw
Those g pens are nifty.
And yes shred, you very much do want one. Good luck finding it tho unless you are in a medical/legal state.
Feb. 24, 2015, is a historic day in the Last Frontier: Alaska becomes the third state in the U.S. in which recreational cannabis use is legalized.
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originally posted by: GoShredAK
originally posted by: Shakawkaw
originally posted by: GoShredAK
I have zero reason not to believe marijuana smoke is actually harmless to the lungs.
Unfortunately, it's not really about what you believe. We need further study. Until then, I've got my g-pen.
Not unfortunate, I'm not claiming anything.
Not sure what that is but I think I want one
originally posted by: WeRpeons
a reply to: toastyr
What do you mean? There are no incidences of cancer from smoking marijuana, it actually has protective properties against it.
Really? I didn't know that. I would think inhaling any kind of smoke over time would eventually cause cancer or some other kind of damage to the lungs.
In a cross-sectional analysis using data from two rounds of the National Health and Nutrition Examination Surveys (NHANES), researchers found that adults aged 18 to 59 who smoked one marijuana cigarette — aka joint — a day were still able to forcibly exhale the same volume of air in one second (known as forced expiratory volume, or FEV1) as someone who didn’t smoke marijuana. Measuring a person’s ability to exhale is called spirometry, and it’s the go-to method for diagnosing respiratory diseases, which impair lung function.
originally posted by: amazing
It is fairly harmless, except for the lungs, in my opinion. Most heavy pot smokers that I know, smoke heavily as well. Double trouble for the lungs.
The only thing I don't like is that people think it's okay to get high before work or with non pot smokers etc. That's not okay. get high in your house and well away from me. I dislike slow, stupid stoned people.
I don't like being around drinkers either for the same issue.
originally posted by: TheJourney
originally posted by: amazing
It is fairly harmless, except for the lungs, in my opinion. Most heavy pot smokers that I know, smoke heavily as well. Double trouble for the lungs.
The only thing I don't like is that people think it's okay to get high before work or with non pot smokers etc. That's not okay. get high in your house and well away from me. I dislike slow, stupid stoned people.
I don't like being around drinkers either for the same issue.
It would be inaccurate to say you automatically become stupid after smoking
originally posted by: cronemel
When approaching a stop sign, a drunk will speed up and blow through it. A stoner stops and waits for it to turn green.