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Prior to the controversy surrounding Agent Orange, there was already a large body of scientific evidence linking 2,4,5-T and 2,4-D to serious negative health effects and ecological damage.[14] But in 1969 it was revealed to the public that the 2,4,5-T was contaminated with a dioxin, 2,3,7,8-tetrachlorodibenzodioxin (TCDD), and that the TCDD was causing many of the previously unexplained adverse health effects which were correlated with Agent Orange exposure.[15] TCDD has been described as "perhaps the most toxic molecule ever synthesized by man".[16] Internal memos reveal that Monsanto Corporation (a manufacturer of 2,4,5-T) had informed the U.S. government as early as 1952 that 2,4,5-T that was contaminated with a toxic chemical.[17]