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transcription of wildtype and codon-optimized Spike open reading frames enables alternative splice events that lead to C-terminal truncated, soluble Spike protein variants. These soluble Spike variants may initiate severe side effects when binding to ACE2-expressing endothelial cells in blood vessels. In analogy to the thromboembolic events caused by Spike protein encoded by the SARS-CoV-2 virus
During the last months many countries have started the immunization of millions of people by using vector-based vaccines. Unfortunately, severe side effects became overt during these vaccination campaigns: cerebral venous sinus thromboses (CVST), absolutely rare under normal life conditions, were found as a severe side effect that occured 4-14 days after first vaccinations. Besides CVST, Splanchnic Vein Thrombosis (SVT) was also observed. This type of adverse event has not been observed in the clinical studies of AstraZeneca, and therefore led immediately to a halt in vaccinations in several european countries. These events were mostly associated with thrombocytopenia, and thus, similar to the well-known Heparin-induced thrombocytopenia (HIT). Meanwhile, scientists have proposed a mechanism to explain this vaccine-induced thrombocytopenia. However, they do not provide a satisfactory explanation for the late thromboembolic events. Here, we present data that may explain these severe side effects which have been attributed to adenoviral vaccines. According to our results, transcription of wildtype and codon-optimized Spike open reading frames enables alternative splice events that lead to C-terminal truncated, soluble Spike protein variants. These soluble Spike variants may initiate severe side effects when binding to ACE2-expressing endothelial cells in blood vessels. In analogy to the thromboembolic events caused by Spike protein encoded by the SARS-CoV-2 virus, we termed the underlying disease mechanism the “Vaccine-Induced Covid-19 Mimicry” syndrome (VIC19M syndrome).
April 8th, 2021: mRNA vaccines may cause your body to churn out PRIONS that “eat your brain” like Mad Cow Disease
The mRNA vaccine works by hijacking your body’s cells and causing them to churn out proteins modeled after the spike proteins in the SARS-cov-2 coronavirus. Since that structure includes prion-like regions, random errors in mRNA sequences — which may be truncated by the human immune system before they reach the ribosomes in the cells — could cause mRNA vaccine recipients to churn out prions in their own bodies. The risk of this was assessed by Dr. J. Bart Classen, who authored a paper in Microbiology & Infectious Diseases: “Covid-19 RNA Based Vaccines and the Risk of Prion Disease.”
originally posted by: MichiganSwampBuck
Are these " C-terminal truncated, soluble Spike protein variants" the mutant prions that will eat our brains from that one outrageous report I made a thread on awhile back?
Titled “COVID-19 RNA Based Vaccines and the Risk of Prion Disease,” the paper in question, published in a journal called ‘Microbiology and Infectious Diseases’ in January, was authored by “J. Bart Classen, MD.”
The paper’s central claim is that Pfizer’s mRNA vaccine “contains sequences believed to induce TDP-43 and FUS to aggregate in their prion-based conformation leading to the development of common neurodegerative [sic] diseases.” In other words, he says certain "letters" in RNA code in the vaccine have the potential to trigger changes to the way particular human proteins (namely TDP-43 and FUS) fold, making them cause disease (here).
Prions are misfolded brain proteins that can cause mad cow disease or bovine spongiform encephalopathy, Creutzfeldt Jakob disease, or CJD, chronic wasting disease in deer and elk, and scrapie in sheep (here).
originally posted by: EvilAxis
originally posted by: MichiganSwampBuck
Are these " C-terminal truncated, soluble Spike protein variants" the mutant prions that will eat our brains from that one outrageous report I made a thread on awhile back?
In a word - no
originally posted by: MichiganSwampBuck
a reply to: EvilAxis
From your link . . .
Having reviewed the paper, which is less than three pages long and provides only three sentences describing its methodology, Dr Albert Hofman, a clinical epidemiologist at the Harvard T.H. Chan School of Public Health (here), told Reuters by phone that the paper provides no evidence for the author’s findings, which he described as “untenable.”
Hofman also stressed that those at greater risk of developing Alzheimer’s, namely individuals over 60, are also at greater risk of becoming seriously ill with COVID-19. Their vaccine need is therefore most urgent, he said...
“It’s hard to believe this paper stood up to the peer-review process,” Dr David Irani, a professor of neurology at the University of Michigan Medical School (here), told Reuters via email.
Echoing Appleby, Irani said that the paper’s author “provides no detail regarding how his analyses were conducted and no actual data for his readers to evaluate for themselves.”
Irani noted that the paper was “rife with ambiguous phrases such as ‘may cause’ and ‘the potential to’ that heighten its speculative tone,” describing the discussion as “straying into areas that are completely unfounded” as Classen “heavily references his own prior publications in a way that identifies him as an anti-vaccine advocate rather than an objective scientific investigator.”
“Experience over the last 9 months has certainly taught us that mRNA vaccines against COVID-19 can cause side effects in some individuals, but there is absolutely no evidence linking them to neurodegenerative disease,” Irani concluded.
originally posted by: butcherguy
When the incubation period for prion diseases run from 5 to 40 YEARS, how would they be able to state that the vaccines don't cause them???