It looks like you're using an Ad Blocker.
Please white-list or disable AboveTopSecret.com in your ad-blocking tool.
Thank you.
Some features of ATS will be disabled while you continue to use an ad-blocker.
HulaAnglers: I remember here in Quebec in the 70's there was secret selective sterilization performed at the discretion of doctors - my little brother was hospitalized for flue like symptoms and treated for meningitis and he is now sterile, I was "accidentally" sterilized by a black Haitian doctoress at 24.
Valproate semisodium (INN) or divalproex sodium (USAN) consists of a compound of sodium valproate and valproic acid in a 1:1 molar relationship in an enteric coated form. It is used in the UK and U.S. for the treatment of the manic episodes of bipolar disorder. In rare cases, it is also used as a treatment for major depressive disorder, and increasingly taken long-term for prevention of both manic and depressive phases of bipolar disorder, especially the rapid-cycling variant. It is also used in the US for the treatment of epilepsy, chronic pain associated with neuropathy, and migraine headaches. Its chemical name is sodium hydrogen bis(2-propylpentanoate). The extended release formulation allows for a single daily dose.
Histone deacetylases (HDAC) are a class of enzymes that remove acetyl groups from an ε-N-acetyl lysine amino acid on a histone. Its action is opposite to that of histone acetyltransferase.
Histone deacetylase inhibitors (HDIs) have a long history of use in psychiatry and neurology as mood stabilizers and anti-epilectics, for example, valproic acid. More recently, HDIs are being studied as a mitigator or treatment for neurodegenerative diseases.[14][15] Also in recent years, there has been an effort to develop HDIs for cancer therapy, and Vorinostat (SAHA) has recently been approved for treatment of cutaneous T cell lymphoma (CTCL). The exact mechanisms by which the compounds may work are unclear, but epigenetic pathways are proposed.[16] In addition, a clinical trial is studying valproic acid effects on the latent pools of HIV in infected persons.[17]
Our data supports the concept that chromatin acetylation and DNA methylation are found in a dynamic interrelation and that the consequences of HDAC inhibitors are not limited to changes in histone acetylation but that they also bring about a change in the state of modification of DNA. The implications of our results on the future therapeutic utilities of VPA in cancer will be discussed.
RESULTS: Sixty-three conventional IVF cycles were performed, 760 oocytes were retrieved, an average of 8.1 +/- 4.8 embryos was obtained, and 2.4 embryos were transferred. Neither the fertilization rate nor the rate of good quality embryos was correlated with the DNA methylation level (r = -0.1 and r = -0.08 respectively; not significant). When sperm DNA methylation was >555 arbitrary units, the pregnancy rate was 33.3% compared with 8.3% in the lower (
Of the other big groups in Australia, Sydney IVF is an unlisted public company, about 75% owned by practitioners, while Melbourne IVF and Queensland Fertility Group have small shareholder registries that also appear dominated by doctors.
CONCLUSIONS: This is the first report of a broad epigenetic defect associated with abnormal semen parameters. Our results suggest that the underlying mechanism for these epigenetic changes may be improper erasure of DNA methylation during epigenetic reprogramming of the male germ line.
Originally posted by andy1033
You guys do you really have a problem with sterialisation, i don't. I think it is the only way to control world population.
I agree with sterialisation but not with depopulation by killing living people or unborn babies.
Do you guys really think this is so bad. Do everyone on the planet really have the right to bring people into this world? Plus before you say it, i have never wanted to have children and never will, so i am not preaching something i do not preach.
People should be against abortion and killing people on mass, but sterialisation, for me is not that bad an idea. i just would prefer it if people where taught to be adults and to make that choose themselves.
Do you guys think mass sterialisation is really that bad, because i do not.
Originally posted by andy1033
You guys do you really have a problem with sterialisation, i don't. I think it is the only way to control world population.
I agree with sterialisation but not with depopulation by killing living people or unborn babies.
Do you guys really think this is so bad. Do everyone on the planet really have the right to bring people into this world? Plus before you say it, i have never wanted to have children and never will, so i am not preaching something i do not preach.
People should be against abortion and killing people on mass, but sterialisation, for me is not that bad an idea. i just would prefer it if people where taught to be adults and to make that choose themselves.
Do you guys think mass sterialisation is really that bad, because i do not.