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Srinivasan explains that the chip is sending electric pulses through the needle into the brain slice, which is passing them on to the screen we're watching. "The difference in the waves' modulation reflects the signals sent out by the brain slice," he says. "And they're almost identical in frequency and pattern to the pulses sent by the chip." Put more simply, this iron-gray wafer about a millimeter square is talking to living brain cells as though it were an actual body part.