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originally posted by: Crackalackin
Honey
3.2. Hesperidin: A Flavonol That May Promote a Healthier Profile of the Microbiota
Some clinical studies have demonstrated the role of polyphenols, supplemented in several food products, in maintaining the intestinal health and preserving microbial homeostasis by promoting the growth of beneficial bacteria and inhibiting the progression of pathogenic bacteria [105]. Indeed, polyphenols and hesperidin can modulate gut microbial composition or functionality, which affects the release of microbial-derived metabolites [106]. Flavonols are active inhibitors against some Gram-negative bacteria, such as Prevotella spp., Porphyromonas gingivalis, Fusobacterium nucleatum, E. coli, Pseudomonas aeruginosa, and Clostridium spp. [107,108] (Figure 3). In addition, hesperidin and other flavonols also inhibit the growth of some Gram-positive bacteria, such as Staphylococcus aureus and Lactobacillus acidophilus [107,108]. Besides their inhibitory capacity, phenolic compounds may modify gut microbiota by selectively promoting the growth of beneficial bacteria of the genera Lactobacillus or Bifidobacterium [109,110].