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originally posted by: lostgirl
First, I'm not anti vaccine - my whole family (myself included) have had the Johnson&Johnson shot...
...but that was before I started coming across a lot of the actual science, much of which is unfortunately being either scrubbed or politicized.
The problem is that my husband is driving me crazy!
No matter what I 'bring to the table' regarding actual facts and figures, if it comes from either side of the political divide, he says it's biased and won't even look at it!
These risks, uncertainties, and other factors include, among others: the fact that there has never been a commercial product utilizing mRNA technology approved for use
The Pfizer-BioNTech COVID-19 Vaccine has not been approved or licensed by the U.S. Food and Drug Administration (FDA), but has been authorized for emergency use by FDA under an Emergency Use Authorization (EUA) to prevent Coronavirus Disease 2019 (COVID-19) for use in individuals 16 years of age and older
There are no specific guidelines for use of messenger RNA (mRNA) vaccines or contraindications to mRNA vaccines.
No large trials of any mRNA vaccine have been completed yet.
The only evidence on safety of mRNA vaccines comes from small phase I and phase II trials of SARS-CoV-2 vaccines, with
follow-up typically less than two months.
Systemic adverse events such as fatigue, muscle aches, headache, and chills are common.
Severe systemic adverse events were reported by 5 to 10 percent of trial subjects.
Localized adverse events such as pain at the injection side are common.
Both systemic and local adverse events usually are resolved within one or two days.
The rate and severity of adverse events appears to be higher for the second dose of vaccine than for the first.
Higher vaccine doses appear to increase the rate and severity of adverse events.
Larger trials of SARS-CoV-2 vaccines are in progress, with results expected in mid-2021.
There is not sufficient evidence to support any conclusions on the comparative safety of different mRNA vaccines.
Direct evidence on the comparative safety of mRNA vaccines and other vaccines is lacking
showed lipid nanoparticles from the vaccine did not stay in the deltoid muscle where they were injected as the vaccine’s developers claimed would happen, but circulated throughout the body and accumulated in large concentrations in organs and tissues, including the spleen, bone marrow, liver, adrenal glands and — in “quite high concentrations” — in the ovaries.
Potential safety concerns that are likely to be evaluated in future preclinical and clinical studies include local and systemic inflammation, the biodistribution and persistence of expressed immunogen, stimulation of auto-reactive antibodies and potential toxic effects of any non-native nucleotides and delivery system components. A possible concern could be that some mRNA-based vaccine platforms54,166 induce potent type I interferon responses, which have been associated not only with inflammation but also potentially with autoimmunity167,168. Thus, identification of individuals at an increased risk of autoimmune reactions before mRNA vaccination may allow reasonable precautions to be taken. Another potential safety issue could derive from the presence of extracellular RNA during mRNA vaccination. Extracellular naked RNA has been shown to increase the permeability of tightly packed endothelial cells and may thus contribute to oedema169. Another study showed that extracellular RNA promoted blood coagulation and pathological thrombus formation170
Development of new vaccine technology has been plagued with problems in the past. The current RNA based SARSCoV-2 vaccines were approved in the US using an emergency order without extensive long term safety testing. In
this paper the Pfizer COVID-19 vaccine was evaluated for the potential to induce prion-based disease in vaccine
recipients. The RNA sequence of the vaccine as well as the spike protein target interaction were analyzed for the
potential to convert intracellular RNA binding proteins TAR DNA binding protein (TDP-43) and Fused in Sarcoma
(FUS) into their pathologic prion conformations. The results indicate that the vaccine RNA has specific sequences
that may induce TDP-43 and FUS to fold into their pathologic prion confirmations. In the current analysis a total
of sixteen UG tandem repeats (ΨGΨG) were identified and additional UG (ΨG) rich sequences were identified. Two
GGΨA sequences were found. Potential G Quadruplex sequences are possibly present but a more sophisticated
computer program is needed to verify these. Furthermore, the spike protein, created by the translation of the vaccine
RNA, binds angiotensin converting enzyme 2 (ACE2), a zinc containing enzyme. This interaction has the potential
to increase intracellular zinc. Zinc ions have been shown to cause the transformation of TDP-43 to its pathologic
prion configuration. The folding of TDP-43 and FUS into their pathologic prion confirmations is known to cause
ALS, front temporal lobar degeneration, Alzheimer’s disease and other neurological degenerative diseases. The
enclosed finding as well as additional potential risks leads the author to believe that regulatory approval of the
RNA based vaccines for SARS-CoV-2 was premature and that the vaccine may cause much more harm than benefit.
You could always start with the study done by the Cleveland Clinic that concluded, without any ambiguity, that people who have had and recovered from COVID-19 gain zero advantages in fighting off reinfection by getting vaccinated--the naturally derived immunity is strong enough (and lasts at least 10 months).
originally posted by: incoserv
Reality is a b***h, and cognitive dissonance is one helluva drug.
WARNING: Libtard who does not know how to express himself in a thoughtful, mature manner and must resort to profanity.
PfizerTrusted Source, Moderna, AstraZeneca, and Johnson & Johnson vaccines work well against the variants, including delta, especially when it comes to preventing severe illness, hospitalization, and death.
Immunity after a previous infection “is highly variable from one person to the next — it may be barely present and not last for long for some persons,” said Dr. Richard A. Martinello, a Yale Medicine infectious diseases specialist and associate professor at Yale School of Medicine.
A small study led by researchers at the University of Oxford found that people who produced weaker immune responses may be more at risk for reinfection from new variants.
But in most cases, the immunity conferred from the previous infection appears to provide good protection against severe illness.
The study details an outbreak that started July 3 in Provincetown, Mass., involving 469 cases. It found that three-quarters of cases occurred in fully vaccinated people. Massachusetts has a high rate of vaccination: about 69% among eligible adults in the state at the time of the study.
It also found no significant different in the viral load present in the breakthrough infections occurring in fully vaccinated people and the other cases, suggesting the viral load of vaccinated and unvaccinated persons infected with the coronavirus is similar.
The good news is that the vaccines continue to be highly effective against the virus in preventing hospitalization and death. For instance, three studies from Canada, Singapore and Scotland have found that the Pfizer vaccine provides more than 90% protection against hospitalization and death.
originally posted by: carewemust
HERE IS A 100% POLITICS-FREE Covid-19 VACCINE
RUSSIA developed a vaccine because it wants the citizens there to live long productive lives, serving the communist party.
The vaccine is rated well: scitechdaily.com...
originally posted by: lostgirl
a 'place' for people to post links to nonpartisan sources of Covid/'vax' science Thank you!