Vaccine Evasive Covid Variants

Yes, get ready for generation 3, 4, and 5 vaccines. It appears that the new variants can resist the antibodies produced by both the vaccines and your natural antibodies from previous exposure.

www.forbes.com...

Studies have shown the P.1 is highly resistant to neutralizing antibodies, whether from vaccines or natural infection. Mutations to the receptor-binding domain, the mechanism which connects to the ACE2 receptor of the human cell, likely drive this resistance.

Recently released data on the Astrazeneca vaccine indicate neutralization efficacy of only 10%. This is notable as the Brazilian, Japanese, and now Philippine variants all bear significant commonality with the South African variant. There is a substantial possibility that the vaccine would struggle with these other variants as well.

Development of new vaccines to cater to these variants is already underway. However, who is to say that those second-generation vaccines will be capable of neutralizing the Japanese or Philippine variant? Perhaps then a third-generation vaccine will be developed, and the game of whack-a-mole continues.

www.forbes.com...

Two doses of the AstraZeneca Covid-19 vaccine were found to have only a 10.4% efficacy against mild-to-moderate infections caused by the B.1.351 South Africa variant, according to a phase 1b-2 clinical trial published on Tuesday in the New England Journal of Medicine. This is a cause for grave concern as the South African variants share similar mutations to the other variants leaving those vaccinated with the AstraZeneca vaccine potentially exposed to multiple variants.

www.cbsnews.com...

Said it before and I'll say it again. This is how our world ends, coughing and gasping for air.

Now we're starting to see the futility of trying to neutralize this thing with vaccines. It is a waste of time and money. Make effort to stay healthy and you are extremely likely to survive infection. Natural immunity is far more efficacious than vaccines.

a reply to: infolurker

The scary thing is I know many, many friends & family members who will probably go along with getting "the new" vaccines if the current ones they've already gotten aren't effective...

It's such a sensitive topic even with the people closest to me in my life, but I also believe in allowing people to make their own choices.

originally posted by: FamCore
a reply to: infolurker

The scary thing is I know many, many friends & family members who will probably go along with getting "the new" vaccines if the current ones they've already gotten aren't effective...

It's such a sensitive topic even with the people closest to me in my life, but I also believe in allowing people to make their own choices.

I know people who would stab a pensioner to get their hands on their first covid jab. Some have deliberately jumped the queue already.
The media has people terrified and the government in its desperation to get the money rolling in and ahead of their economic rivals are only too happy to play along.

People who keep going to give these pharma companies money are idiots, plain and simple, they're substituting a healthy immune system for an artificial one.

Also, trying to use a leaky vaccine amidst a running pandemic should be a war crime, at the very least mass manslaughter.

Now you know the real reason behind the shutdowns and the wearing of masks. To give the virus time to evolve.

a reply to: infolurker
All this while I've been hearing for a some time that the overuse of antibiotics has helped to create resistant bugs which cause more problems than the ones you took the antibiotics for to start with.

Maybe that's a case of apples v oranges but I suspect the same or similar outcome eventually.

has the death rates gone up with generally healthy people?

If it hasn't then I still dont see the point.

This information is with the AstraZeneca vaccine which is substantially different again in how it is made than either the Pfizer and Moderna ones or the J&J one. So just because the AZ vax isn't offering good coverage doesn't mean the other three are going to be the same way when it comes to the variants.

originally posted by: ketsuko
This information is with the AstraZeneca vaccine which is substantially different again in how it is made than either the Pfizer and Moderna ones or the J&J one. So just because the AZ vax isn't offering good coverage doesn't mean the other three are going to be the same way when it comes to the variants.

Although these vaccines work differently than the flu vaccine, they are both trying to prevent viral infection. The normal flu vaccine is only 10-50% effective due to the variability that these viruses are capable of. billions of dollars later we may realize it's just not worth it to go the vaccine route against certain viruses. In the mean time let's be thankful the human immune system is about 99% capable of eliminating this thing.

a reply to: cooperton

The reason the regular flu vaccine is only partially effective in most years is because the flu strains mutate.

Again - the technology used to make the Pfizer, Moderna, and even the J&J are different than the tech used to make the flu vaccine meaning we don't know how those will handle the variant strains. The AstraZeneca is made much more like the flu vaccine, so it stands to reason that it would handle the variant strains about as well.

The AstraZeneca uses a weakened strain of a very similar type of coronavirus to the one causing COVID-19. The variants could have mutated in a critical way to lessen the effectiveness of the antibodies provoked by that strain.

Pfizer and Moderna's vaccines don't use weakened virus at all. They work in an entirely different way. In order for the variant strains not to be targeted, very specific proteins common to most coronaviruses would have to mutate in very specific ways.

Now there are very sound reasons to be suspicious of what Pfizer and Moderna's vaccines do in terms of safety long-term especially because they are toying with the immune system in ways we haven't previously done before, but in terms of losing their effectiveness because the strains mutate a little bit? No. They shouldn't have that particular problem. At least, they shouldn't very easily.

This is exactly what Geert Vanden Bossche predicted, that giving these vaccines in the height of a pandemic would create vaccine resistance super covid strains due to immunity escape

originally posted by: cooperton
Now we're starting to see the futility of trying to neutralize this thing with vaccines. It is a waste of time and money. Make effort to stay healthy and you are extremely likely to survive infection. Natural immunity is far more efficacious than vaccines.

Never been a vaccine for a corona virus. That stat hasn’t changed.