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Background
Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
Results
We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
Conclusion
Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
That said, it could conceivably done by President Trump I'd imagine. My question is why does Trump keep him around? Makes me wonder about Trump.
That said, it could conceivably done by President Trump I'd imagine. My question is why does Trump keep him around? Makes me wonder about Trump.
originally posted by: americanbuffalo1
I don't think highly of Fauci myself and find him to be a 'compromised expert' of whom his words mean nothing as he has spoken from both sides of his mouth often enough.
That said, it could conceivably be done by President Trump I'd imagine. My question is why does Trump keep him around? Makes me wonder about Trump.
originally posted by: americanbuffalo1
a reply to: projectvxn
Trump is stuck with him then. I suppose that's something to consider. However he needs to go away nonetheless.
Are there any of these studies around on HCQ?
originally posted by: projectvxn
originally posted by: americanbuffalo1
a reply to: projectvxn
Trump is stuck with him then. I suppose that's something to consider. However he needs to go away nonetheless.
I think, based on all we know now, that Trump could fire him and have more than enough justification.
Lying to the country and causing death should be at the top of the list to fire a scum bag like Fauci.
Detailed Description:
Since hydroxychloroquine is a low cost and safe anti-malaria drug that has proven effects against COVID-19 in vitro.
Both of these drugs have been studied significantly for their prophylactic attributes against SARS-like viruses. Most of the use and studies are outside of the US.
The U trial was the first in the world to assess whether hydroxychloroquine could prevent the onset of COVID-19 in people exposed to the novel coronavirus that causes it, and the first placebo-controlled double-blind study of the drug’s effect on COVID-19. Blinding means that patients didn’t know whether they took vitamins or drugs, and researchers didn’t know either.