Ageing in Human Cells Successfully Reversed in the Lab

The Conversation.com

Ageing can be viewed as the progressive decline in bodily function and is linked with most of the common chronic diseases that humans suffer from, such as cancer, diabetes and dementia. There are many reasons why our cells and tissues stop functioning, but a new focus in the biology of ageing is the accumulation of “senescent” cells in the tissues and organs.

Senescent cells are older deteriorated cells that do not function as they should, but also compromise the function of cells around them. Removal of these old dysfunctional cells has been shown to improve many features of ageing in animals such as the delayed onset of cataracts.

Another good source of information is this short video by Kurzgesagt – In a Nutshell



Research done on mice has led to successful experiments in human cells. The reversal of aging does not necessarily mean that we will live forever, or that we even could, but it does mean that we can increase how long we are disease-free, how much of our lives we can enjoy actively, and yes, even buy more time-though again, not an infinite amount of time.

To scientists working in this particular field, aging is viewed as a degenerative disease that causes all kinds of awful conditions until the organism that is aging dies, as we live longer and longer lives, reversing the effects of aging may be the most effective way to treat the conditions most common to the elderly population.

There is a new age around the corner.

a reply to: projectvxn

Great!

This technology needs to be perfected before the Great Purge begins.

We're all screwed.

a reply to: projectvxn

I need this now.

a reply to: projectvxn

There is a new age around the corner.

Nice pun bro.

a reply to: projectvxn

There have been quite a few studies over the last few years in this regard. Its pretty exciting to consider, agents like resveratrol and NADH+ have shown to be quite promissing towards the anti aging effects being researched. It always has to do with detoxification of cells, keeping them more viable. Basically, it seems our bodies could use regular oil changes.

Look forward to watching your video.

Unfortunately, this will be reserved for a select few ( elite, rich, famous etc. but mainly rich) for a long long time, if not forever. Us peons will be left to work, age, and die as usual.

a reply to: projectvxn

Good read.

By using a “molecular postcode” we have been able to deliver the molecule directly to the mitochondria

It's crazy they can do that with a “molecular postcode”!?!

a reply to: BlueJacket

Hate to say it, but reservatrol has been debunked. Currently no reason at all to believe it is the cause of the French Paradox.

Lots of other promising developments in the anti aging crusade though! I think we might want to temper our enthusiasm though, I find it hard to believe such things will ever make it down to the masses. Until overpopulation and resource management issues are dealt with, it's simply impractical (and suicidal) for the elites to let everyone live forever.

a reply to: nightbringr

Fair enough, guess Im using examples of studies rather than pointing to an actual success. NADH+ has some promise at least some relevent results with mice.

Autophagy is happening in every body although less so as we age. It can be enhanced some with fasting and diet.

Autophagy is the natural, regulated mechanism of the cell that disassembles unnecessary or dysfunctional components. Autophagy allows the orderly degradation and recycling of cellular components. Wikipedia

en.wikipedia.org...



Mice studies do not always relate to our complicated chemical structure.

Nice thread though Thanks.

originally posted by: myselfaswell
a reply to: projectvxn

There is a new age around the corner.

Nice pun bro.

I do what I can.

a reply to: projectvxn

Does this affect the deterioration of our telomeres?

a reply to: SorrowSong

It certainly does.

a reply to: projectvxn

If it turns out to be the Elixir-of-life, it should be illegal for politicians and lawyers and banksters to have access to it.

probably Kiwis too, but thats not important for the moment.

originally posted by: Sublimecraft
a reply to: projectvxn

If it turns out to be the Elixir-of-life, it should be illegal for politicians and lawyers and banksters to have access to it.

probably Kiwis too, but thats not important for the moment.

To be perfectly honest, no one should have this.

a reply to: nightbringr

Why?

I want to live a longer healthier life, why would you take that away?

Oh wait, you think this is a movie where there is this race against time to get the elixer to make sure it doesn't "fall into the wrong hands", because we all know the rights hands always get the girl...

Relax man, this won't make us immortal. If you had read the post and supporting information you'd know that.

a reply to: SituationNAFU

Biochemical analysis.

The truth is, most people have no idea what it really takes to get research like this done, even with tons of funding and resources, research like this can be long and arduous. Big Pharma is certainly not all-powerful and money is, as of yet, no match for the complexity of our biochemical machine.

originally posted by: projectvxn
a reply to: SorrowSong

It certainly does.

I watched the video and read the OP, it didn’t explain how. Would you elaborate please?

a reply to: SorrowSong

There is a growing body of work

That has linked senesence with telomere shortening.

originally posted by: projectvxn
a reply to: nightbringr

Why?

We would kill ourselves off in no time. Overpopulation is already a thing, it would be exponentially worse if our reproductive years were increased even twofold.

Perhaps we need to work out a solution? All those who sign on for significant life extension are made sterile until a time comes that we can comfortably support the massive burden having a much extended life and reproducing would cause.