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Causes Chromosome 6 Ring results from deletion (monosomy) of chromosomal material from the long arm (q) and short arm (p) of chromosome 6 and a joining of the ends to form a ring. Chromosomes are found in the nucleus of all body cells. They carry the genetic characteristics of each individual. Pairs of human chromosomes are numbered from 1 through 22, with an unequal 23rd pair of X and Y chromosomes for males and two X chromosomes for females. Each chromosome has a short arm designated as “p,” a long arm identified by the letter “q,” and a narrowed region at which the two arms are joined (centromere). Chromosomes are further subdivided into bands that are numbered.
Affected Populations Since Chromosome 6 Ring was originally described, approximately 23 cases have been reported in the medical literature. In observed cases, males appear to be affected slightly more frequently than females.xt
Diagnosis In some cases, Chromosome 6 Ring may be suggested before birth (prenatally) by specialized tests such as ultrasound, amniocentesis, and/or chorionic villus sampling (CVS). During fetal ultrasonography, reflected sound waves create an image of the developing fetus, potentially revealing certain findings that suggest a chromosomal disorder or other abnormalities. With amniocentesis, a sample of fluid that surrounds the developing fetus is removed and analyzed, while CVS involves the removal of tissue samples from a portion of the placenta. Chromosomal analysis performed on such fluid or tissue samples may reveal the presence of Chromosome 6 Ring.
In affected individuals with hydrocephalus, shunting may be required to remove excess cerebrospinal fluid (CSF). Shunts are specialized devices that drain excess CSF away from the brain to another part of the body for absorption into the bloodstream. For individuals affected by seizures, treatment may include the administration of anticonvulsant medications to help prevent, reduce, or control seizures. Early intervention may be important in ensuring that affected children reach their potential. Special services that may be beneficial include special education, physical therapy, and/or other medical, social, and/or vocational services. Genetic counseling will also be of benefit for affected individuals and their families. Other treatment for this disorder is symptomatic and supportive.
In the event of mosaicism a genetic change may not be observed in DNA from all tissue types and in this case the c.1710C>T mutation was absent in the affected father's blood leucocytes. As sequencing would normally only identify a mutation if it was present at a level of 10–20% of the total DNA, further sequencing analysis of multiple amplicon clones was performed and confirmed that mutation is unlikely to be present in the father's leucocytes down to a level of 5% of the normal allele. Germline mosaicism would result in vertical transmission of the mutated gene, with offspring displaying 100% penetrance in the case of an autosomal dominant disorder. Furthermore, the risk for the daughter of passing the mutant allele to her children would be 50%, as for any other individual affected by an autosomal dominant condition.
De novo, a term for any method that makes predictions about biological features using only a computational model without extrinsic comparison to existing data. In this context, it may be sometimes interchangeable with the Latin term ab initio. De novo mutation, an alteration in a gene that is present for the first time in one family member as a result of a mutation in a germ cell (egg or sperm) of one of the parents or in the fertilized egg itself [1] De novo transcriptome assembly, the method of creating a transcriptome without a reference genome De novo synthesis of complex molecules from simple molecules in biochemistry De novo protein design, the creation of a protein sequence that is not based on existing, natural sequences. De novo protein structure prediction, the prediction of a protein's 3D structure, based only on its sequence. De novo hybrid, an organism newly derived from two distinct parent taxa (i.e., an F1 hybrid or hybrid not far removed from the F1 generation).
Chromosome 6 Ring is a rare disorder in which there is loss (deletion) of chromosomal material from both ends of the 6th chromosome and joining of the ends to form a ring. Associated symptoms and findings may vary greatly, depending upon the amount and location of lost chromosomal material and other factors. For example, there have been some reported cases in which children with Chromosome 6 Ring have few physical abnormalities and normal intelligence. However, many with the chromosomal abnormality are affected by growth retardation; varying degrees of mental retardation; mild to severe delays in the acquisition of skills requiring the coordination of mental and physical activities (psychomotor retardation); and/or various abnormalities of the skull and facial (craniofacial) region.
edit on 11-4-2016 by dianashay because: (no reason given)
King James Bible Here is wisdom. Let him that hath understanding count the number of the beast: for it is the number of a man; and his number is Six hundred threescore and six.
originally posted by: dianashay
a reply to: gator2001
I don't think so, I think it refers to the mark being an (easily distinguishable) change, of the beast (or from the beast).
Humans as Gods, no, or human satans, no. The majority, I assume would be easily manipulated slaves, or for who knows what other purpose to keep around.