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originally posted by: Vdogg
a reply to: AlphaHawk
So proprietary may be a better word than what CNN used. The issue remains the same however. We have an experimental treatment that shows promise that it appears that the NIH, in concert with Mapp bio pharmaceutical, withheld until the time that 2 Americans were infected. This wasn't even offered as a possibility a little more than a week ago. Everyone was saying there is no cure/vaccine/etc. One question though, If this is not a cure then what do we call it if these two doctors make a full recovery?
bahhh more western quackery i tells ya,,,
No side effects of the antibodies were observed in the surviving animals.
MB-003 was developed through a decade-long collaborative effort between private industry and the U.S. government, with funding from the Defense Advanced Research Projects Agency (DARPA), the National Institutes of Health (NIH), and the Defense Threat Reduction Agency (DTRA).
“Our facility can produce these proteins in two weeks at a substantial reduction in cost to other production methods,” said Bratcher. “This advanced method of manufacturing allows us to address needs quickly and inexpensively.”
According to Zeitlin, the next step in the drug development process would be to more extensively test the safety of the antibodies in animals. Once that is established, the safety of the antibodies would need to be assessed in human volunteers. Ultimately, a large efficacy study in non-human primates and a larger safety study in humans would be required for Food and Drug Administration (FDA) licensure of the product.
originally posted by: NavyDoc
originally posted by: rickymouse
I guess there is a sales pitch going on here. I wonder how much that drug is going to set people back if they need it?
It's not a drug. It is an experimental serum derived from the infected that survived.
Dr. Kent Brantly was given the medication, ZMapp, shortly after telling his doctors he thought he would die, according to a source familiar with his case. Within an hour, doctors say his symptoms -- labored breathing and a widespread rash -- dramatically improved. Nancy Writebol, another missionary working with Samaritan's Purse, received two doses of the medication and has also shown significant improvement, sources say. As there is no proven treatment and no vaccine for Ebola, this experimental drug is raising lots of questions. Who makes the drug? Why isn't there an Ebola vaccine? The drug was developed by the biotech firm Mapp Biopharmaceutical Inc., which is based in San Diego. The company was founded in 2003 "to develop novel pharmaceuticals for the prevention and treatment of infectious diseases, focusing on unmet needs in global health and biodefense," according to its website. Mapp Biopharmaceutical has been working with the National Institutes of Health and the Defense Threat Reduction Agency, an arm of the military responsible for weapons of mass destruction, to develop an Ebola treatment for several years. Are there other experimental Ebola drugs out there? Yes. In March, the NIH awarded a five-year $28 million grant to establish a collaboration between researchers from 15 institutions who were working to fight Ebola. "A whole menu of antibodies have been identified as potentially therapeutic, and researchers are eager to figure out which combinations are most effective and why," a news release about the grant said. Tekmira, a Vancouver-based company that has a $140 million contract with the U.S. Department of Defense to develop an Ebola drug, began Phase 1 trials with its drug in January. But the FDA recently halted the trial, asking for more information.
originally posted by: UnBreakable
a reply to: Vdogg
After it's proven that the vaccine works on the two Americans, Mapp Bio. will stand to make a few billion $ at 1,000 $/shot here in the USA. They know they can't make any money from any west African countries, therefore hundreds of Africans are expendable. Ah, I long for the days of Jonas Salk, who gave his vaccine for polio without the thought of making money or big pharma getting involved. This is why they'll never trot oui the cure for cancer publicly, although it's been cured in a lab. No money to be made. They make big bucks on chemo drugs.