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In the case of one patient in a drug-induced coma, and in subsequent experiments on cats, the researchers found that after deepening the coma by administering a higher dose of drugs, the silent brain started showing minimum but widespread neural activity across the brain
However, it's plausible that long periods of complete inactivity could result in loss of connections between neurons. A coma state such as the one discovered in the new experiments may better protect neural tissue, as it maintains some minimum activity throughout the brain, the researchers said.