Seems there is something going on with Mr. Chappelle.
Being heckled to the point of a show disruption happened twice in Knoxville, Tennessee in June.
Knoxville hecklers take over Dave Chappelle's stage
Makes me think there is some sort of concerted effort. Someone with a grudge maybe or (hate to think it) a publicity stunt?
Here is his interview with Oprah, 45 minutes long:
Dave Cheppelle (hottest comedian in the country walks away)