posted on Jul, 23 2013 @ 12:03 AM
reply to post by intergalactic fire
You know that the study did not use GMO plants, right? You know that Bt toxins are used as pesticides in organic farming, right?
Anyway, about the claims:
Now, the study states that the biopesticides engineered into crops like corn, soy, sugar cane, etc. carry what is known as Bacillus Thuringiensis
(Bt), also called Cry-toxins, which contribute to all sorts of health problems including:
•Hematological malignancies (blood cancers), i.e. leukemia
•Suppression of bone marrow proliferation
•Abnormal lymphocyte patterns
What the study actually states:
1) Some blood abnormalities found after large doses of Bt toxin crystals.
2) No indication of leukemia
3) No "suppression of bone marrow proliferation" but a reduction in the production of red blood cells. Again, after large doses of Bt toxin
4) Some increase in white blood cell production. After large doses of Bt toxin crystals.
Interesting though, the study was submitted to Food Chem Toxical (a well established journal) and withdrawn last year.
Since the Journal of Hematology & Thromboembolic Diseases is a brand new journal, maybe that has something to do with it.
Yet another poorly designed experiment which does not show that Bt toxin (much less GMOs) are harmful.
Just like so many other anti-GMO papers pushed by anti-GMO groups, the sample size is far too small. You cannot achieve a statistically
significant set of results using only three mice of each sex for each group, especially considering the historical incidences of these blood disorders
in the Swiss Albino Mice is not reported.
If the Bt delta endotoxin expressing bacteria did cause various blood disorders, then you would expect to see a relationship between the dose and
the response, however we don’t see this in the paper. For example it reports a “U-shaped” dose response curve with high responses at both low
and high levels of Cry1Ac after 24 hours. That the mice fed the low levels of Cry1Ab had the highest response, while all levels of Cry1Aa had the same
response over a 24 hour period.
Bt spores are widely used in agriculture. But they are not genetically modified to produce toxins. The recombinant proteins are produced by GM
plants. Therefore, there is no reason to assay GM Bt spores as alias to GM plants.
The language used in the paper is not clear. The authors claimed to have used spore-crystals. This is not the same as having used purified Cry
proteins: to the best of our knowledge, the spore-crystals mentioned here are indeed lyophilized spores for Cry-producing Bt strains, as described in
the first paragraph of the Methodology section.
Surprisingly, the authors do not have a fundamental control: a spore not expressing a toxin or expressing an unrelated toxin. The only controls
were water (negative) and cyclophosphamide (positive). The lack of this third control prevents any conclusion on the true effect of the toxins on the
animals, since all other spore molecular components could also affect the mice in such unusual high concentration as those directly applied to the
digestive system in these ill-designed assays.
edit on 7/23/2013 by Phage because: (no reason given)