For me, I take a certain painkiller a few times, and it's ineffective. Tylenol doesn't work for me. None of that does. I had a prescribed
painkiller after ankle surgery a year ago, and while it was effective, it made me dizzy and nauseous, so I said forget it.
My ankle STILL hurts and it's been 14 months since my surgery--had screws, pins, and staples put in to freeze this one ankle joint.
I agree, the same medication/supplement oftentimes does different things to/for different people.