As we all know, there are many threads on ATS which advise us of the dangers of ingredients in our foods. I, like many other people, have tried to
cut down and eliminate as many "bad" things as possible. But I am beginning to realize that it is practically IMPOSSIBLE to get ahead of the
toxins. I am in the U.S., but many countries around the world are dealing with this issue.
I was reading a news blurb this morning which refreshed my memory and spurred me to start this thread.
80% of Pre-Packaged Foods in America Are Banned in Other Countries
I wanted to make a place where we can highlight the things we know or learn on this subject, so that anyone who is looking into improving their food
quality, or trying to learn what additives to avoid, has a place to look.
I find it almost ridiculous when I review additives to common foods. One of my first battles was the additive Polysorbate 80
What Is Polysorbate 80?
Polysorbate 80, also known as polyoxyethylene sorbitan monooleate or Tween™ 80, is an amber-colored, viscous liquid with a slightly bitter taste. It
is used primarily as an emulsifier in food products, cosmetics, vitamins, medicines, and vaccines. The product is a derivative of sorbitol and oleic
acid, and is manufactured worldwide
I need to add here that this substance is known by MANY names: also known as polyoxyethylene sorbitan monooleate or Tween™ 80, Darbepoetin alfa ,
(x)-sorbitan mono-9-octadecenoate poly (oxy-1,2 ethanediyl),
POE (80) sorbitan monooleate, E433.
In the 1980s, Polysorbate 80 was put forward as a potential cure for baldness, and was initially well received; however, in 1986, a lengthy hearing
involving manufacturers, the United States Food and Drug Administration (FDA), the Federal Trade Commission (FTC), and the US Postal Service, a court
ruling prevented manufacturers from making anti-baldness claims
There has been some controversy over the potential health risks of Polysorbate 80. The primary concern involves injection of the chemical into the
body, and a study in 1993 showed that its injection into baby female rats resulted in malformed reproductive organs. Years later, reports of this
study caused many to question if this compound was safe when used in flu vaccines for the H1N1 virus.
Obviously, this article is a simple, informative one. It does not delve too deeply into the studies pertaining to this ingredient. It is included in
many injectibles such as: Rhogam, Gardasil, Quadracel, Flu Vaccines, Infant vaccines, Depo Provera. And more, of course.
Polysorbate 80 (brand names include Alkest, Canarcel and Tween, which is a registered trademark of ICI Americas, Inc.) is a nonionic surfactant and
emulsifier derived from polyethoxylated sorbitan and oleic acid, and is often used in foods. Polysorbate 80 is a viscous, water-soluble yellow liquid.
The hydrophilic groups in this compound are polyethers also known as polyoxyethylene groups which are polymers of ethylene oxide. In the nomenclature
of polysorbates, the numeric designation following polysorbate refers to the lipophilic group, in this case the oleic acid (see polysorbate for more
detail). Polysorbate 80 is often used in food and other products as an emulsifier.
Many people don't like Wikipedia, and I understand, but sometimes it can lead you to more information. For instance, Polysorbate 80 is a nonionic
surfactant (detergent, foaming agent).
This substance is added to Ice Cream (except the organic or some of the high end brands), Sweet Pickle Relish (the only brand I have found on the
shelves without it was produced in India) frozen Pizza and many, many more.
It is difficult to find in depth information on Polysorbate 80. In fact, articles that were more detailed three years ago, I cannot find now. Others
have been on the same quest and one article by a private party has a lot of the info outlined:
Dangerous Food Additives - How Polysorbate 80 Could Be Harming Your Health
This author lists side effects including Allergies, Gastrointestinal Problems, Fertility Issues and Tumor Growth. A private party's opinion you say.
Ok. Let us look at a professional report.
Polysorbate 80 is used as a solubilizing agent in IV formulations of the antiarrhythmic drug amiodarone. Rare case reports of liver toxicity have been
published suggesting polysorbate 80 may contribute to liver toxicity with the IV formulation of amiodarone. The package labeling of amiodarone warns
that polysorbate 80 is also known to leach DEHP (dioctyl phthalate) from PVC and dosing recommendations should be followed closely.
Granted, this is talking about IV therapy. But, notice that it acknowledges the leaching capability of the substance when interacting with PVC
(plastic). Our food these days is commonly packaged in plastic cartons, plastic coated cardboard, and plastic lined cans (BPA). How great a leap is
it to say that this is of concern? OK
Let us look at one more source which provides copious links on the subject:
Tween 80 (Polysorbate 80) -- Polyoxyethylene Sorbitan Monooleate (polyoxyethylenesorbitan monooleat)
Polysorbate 80 and Histidine, a marriage of disaster by Cynthia A. Janak
"Polysorbate 80 is a very effective surfactant used to trick and open up the blood brain barrier (Lannone, Sun, Kreuter and Tianbin for starters) ,
and allow nano-drugs to be dragged through into the brain."--Hilary Butler
My suggestion to those of you who are still interested by this point, is to read every link I have presented. I think you will find that there are
many ways that this substance can be detrimental, both by consumption and injection. Polysorbate 80 is used as an emulsifier, a stabilizer and an
An excipient is generally a pharmacologically inactive substance formulated with the active ingredient ("API") of a medication. Excipients are
commonly used to bulk up formulations that contain potent active ingredients (thus often referred to as "bulking agents," "fillers," or
"diluents"), to allow convenient and accurate dispensation of a drug substance when producing a dosage form. They also can serve various
therapeutic-enhancing purposes, such as facilitating drug absorption or solubility, or other pharmacokinetic considerations. Excipients can also be
useful in the manufacturing process, to aid in the handling of the active substance concerned such as by facilitating powder flowability or non-stick
properties, in addition to aiding in vitro stability such as prevention of denaturation over the expected shelf life. The selection of appropriate
excipients also depends upon the route of administration and the dosage form, as well as the active ingredient and other factors.