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Originally posted by ibiubu
Are you joking? The Islets of Langerhans are in the Pancreas.
Originally posted by beezzer
reply to post by siluriancryptic
Alzheimer's is caused by a Complement Cascade initiated from the A-Beta Amyloid (at a specific molecular weight) created by a difference in tertiary folding.
The blood/brain barrier would not let in something as massive as a spyrochaete.
Unless you are willing to share a peer-reviewed paper that I am unaware of.
Originally posted by beezzer
reply to post by Advantage
Thanks. A source here; lookingatlyme.blogspot.de...
Now I just did a quick read, but from what I gathered, McDonald is lumping in general neurodegenerative patterns together.
Alzheimer's affects the hippocampal region of the brain while the neurodegenerative illustrations shown by McDonald affect any number of the regions of the brain.
So it's like saying, all Alzheimer's is neurodegenerative, but not all neurodegenerative diseases is Alzheimer's.
As for the blood/brain barrier. Anything above a mw of 400 has a really hard time getting through. Those with compromised immune systems or other underlying health issues do have larger "gaps" that could possibly accommodate something(s) larger. But that again is a symptom of a larger health issue. Not the cause.
Just flying by the seat of my pants here. I haven't had to think about this stuff in a while.
Originally posted by jtma508
reply to post by beezzer
Wrong on the blood-brain barrier comment Wrabbit. Lyme disease (borrelia spirochete) can and does penetrate into the CNS causing massive problems for the patient. Take it from somebody who has been there. The borrelia organism is able to penetrate into just about any organ in the body including directly into immune system cells. Two procedures performed on people with advanced Lyme disease (not caught or treated early in the infection) are an MRI and a LP (lumbar puncture).