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Four thousands of years, our thirst for the legendary Fountain of Youth has been nearly as strong as our propensity for perpetuating the myth.
As we age, our normal antioxidative system struggles to take care of our cells. That's when SIRT3 can provide a well-needed boost to our antioxidant system. Unfortunately, SIRT3 levels diminish with age, so eventually our system is engulfed in degeneration.
"Aging is just an accumulation of damage," said Chen. "If you think that way, then it's probably not reversible, because cells are already damaged and no longer functional. But what we show here is that oxidative stress-induced damage, in fact, is reversible."
Originally posted by xszawe
From this flow now comes word that biologists from the University of California, Berkeley have tapped an influential longevity gene that can reverse cell degeneration associated with aging. That's right, they're not just offering a sip from the fountain, they're turning back the clock at the molecular level
rest of article at link
www.disclose.tv...edit on 1-2-2013 by xszawe because: (no reason given)
Sirtuins (SIRTs) are NAD(+)-dependent deacetylases that catalyze the hydrolysis of acetyl-lysine residues. They play an important role in many physiological and pathophysiological processes, such as the regulation of lifespan and the prevention of metabolic diseases. In this study, we analyzed the effect of resveratrol on the gene expression levels of SIRT1, SIRT3, SIRT4, PGC1α, and NAMPT, as well as its effect on NAD(+) and NADH levels, in the liver of non stressed or non impaired wild-type zebrafish. Semiquantative RT-PCR assays showed that resveratrol did not change the mRNA levels of SIRT1 and PGC1α but decreased the expression levels of the SIRT3, SIRT4, and NAMPT genes. The decrease in NAMPT mRNA levels was accompanied by an increase in NADH levels, thereby decreasing the NAD(+)/H ratio. Taken together, our results suggest that resveratrol plays a modulatory role in the transcription of the NAMPT, SIRT3, and SIRT4 genes. Zebrafish is an interesting tool that can be used to understand the mechanisms of SIRTs and NAMPT metabolism and to help develop therapeutic compounds. However, further investigations using healthy experimental animals are required to study the modulation of the SIRT and NAMPT genes by resveratrol before it is used as a nutraceutical compound in healthy humans.
Originally posted by elouina
Just run out and buy yourself some pure trans-Resveratrol. And not the stuff you find in the drug stores. The stuff works wonders but costs aout $1-2 a day depending on dosage. I think 500 mg is plenty.
Originally posted by ErgoTheConclusion
This article makes me consider that the metaphorical "mark of the beast" could be some sort of device or genetic marker required in order to have "eternal physical life".
Those who don't accept it will simply die off and be forgotten within a normal lifetime and not even have to be killed. In fact the whole thing could be turned into some sort of party where those who have decided to "stay on" will celebrate and well wish those who have decided to "move on", etc. Considering the multi-century patience of the supposed NWO plan, what's another 50ish years waiting for all those without the mark to die off before really kicking the plan into gear with those now dependent on you?
Everyone would be so happy because it wouldn't be war and violence while accomplishing the same end result of wiping out anyone willing to die for their belief (for real this time!) and keeping everyone else around now as more or less dependent physical people requiring this "mark" to continue to live or buy/sell land, etc... aka the "mark" being this "genetic marker".
Huh.
Interesting choice to give someone. Especially if it's actually been possible for a few thousand years so long as you were willing to keep your mouth shut.edit on 1-2-2013 by ErgoTheConclusion because: (no reason given)
Originally posted by Aleister
Originally posted by elouina
Just run out and buy yourself some pure trans-Resveratrol. And not the stuff you find in the drug stores. The stuff works wonders but costs aout $1-2 a day depending on dosage. I think 500 mg is plenty.
What does it "do"? Never heard of it before. Would Ponce de Leon be spending his gold to get it? Does it relate to this thread in terms of working with those cute little guys, our mitochondria? Thanks.
Originally posted by chr0naut
It quite clearly states in The Revelation of Christ to John, that the "Mark of the Beast" is a commerce aid, without it you cannot buy and sell.
This does not sound like a genetic marker for longevity.