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Questions have been raised about the use of this anti-malarial drug for illegal and secret experiments. High dosages were given to all detainees, including David Hicks, to stop the spread of malaria. But it was not given to staff brought into the centre from malaria-endemic countries. Army doctor Remington Nevin said mass administration of the drug in such high doses to people who are asymptomatic or uninfected was akin to ''pharmacologic waterboarding''. Anti-malaria drugs were used for experimental research by the CIA in the 1950s under its MK-ULTRA mind control program, according to research by independent news outlet Truthout. The US Food and Drug Administration product guide says it can cause mental health problems, including anxiety, hallucinations, depression and unusual behaviour. It has been linked to brain injuries, suicidal and homicidal thoughts, depression and anxiety.