11 hours into the flight, the crew had been awake for over 16 hours. Before launch, NASA had decided that at least one crew member should be awake at all times to deal with any issues that might arise. Borman started the first sleep shift, but between the constant radio chatter and mechanical noises, he found sleep difficult.[25] Apollo 8 S-IVB rocket stage, shortly after separation About an hour after starting his sleep shift, Borman requested clearance to take a Seconal sleeping pill. However, the pill had little effect. Borman eventually fell asleep but then awoke feeling ill. He vomited twice and had a bout of diarrhea that left the spacecraft full of small globules of vomit and feces that the crew cleaned up to the best of their ability. Borman initially decided that he did not want everyone to know about his medical problems, but Lovell and Anders wanted to inform Mission Control. The crew decided to use the Data Storage Equipment (DSE), which could tape voice recordings and telemetry and dump them to Mission Control at high speed. After recording a description of Borman's illness they requested that Mission Control check the recording, stating that they "would like an evaluation of the voice comments".[26] The Apollo 8 crew and Mission Control medical personnel held a conference using an unoccupied second floor control room (there were two identical control rooms in Houston on the second and third floor, only one of which was used during a mission). The conference participants decided that there was little to worry about and that Borman's illness was either a 24-hour flu, as Borman thought, or a reaction to the sleeping pill

Originally posted by MrUncreated
In space, no one can hear you poop!